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Official Full Name ankyrin repeat and SOCS box containing 11
Background The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms ASB11; ankyrin repeat and SOCS box containing 11; ankyrin repeat and SOCS box protein 11; DKFZp779E2460; ASB-11; ankyrin repeat domain-containing SOCS box protein ASB11; MGC119168; MGC119169
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ASB11-349H Recombinant Human ASB11 Protein, His-tagged E.coli His
    Human ASB11-884H Recombinant Human ASB11 protein, GST-tagged Wheat Germ GST
    Mouse ASB11-2007M Recombinant Mouse ASB11 Protein Mammalian Cell His
    Rhesus Macaque ASB11-422R Recombinant Rhesus monkey ASB11 Protein, His-tagged Mammalian Cell His
    Zebrafish ASB11-12807Z Recombinant Zebrafish ASB11 Mammalian Cell His

    asb11 involved in several pathways and played different roles in them. We selected most pathways asb11 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with asb11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System RAPGEF4; CD300LF; TRIM41; TRIM39; RAP1GAP2B; MGC174152; LAIR1; GM11711; B2ML; CTSLL
    Antigen processing: Ubiquitination &amp ATG7; TPP2; ASB4; UBR2; UBE2V2; UBE2E3; NPEPPS; UBR1; FBXO3; ASB2
    Proteasome degradation SPSB4; UBE2E3; STUB1; RNF34; LRSAM1; TRIM11; RNF138; NPEPPS; UCHL3; ASB13
    Class I MHC mediated antigen processing &amp RBCK1; UBE2F; SEC23A; FBXO27; LRRC41; ERAP2; ASB13; SPSB4; SH3RF1; DZIP3
    presentation SPSB4; SPSB2; DZIP3; RBCK1; ASB10; STUB1; TRIM69; ERAP1; RNF19B; ARIH2
    Immune System CD200R1; KIF3B; SIGLEC8; BTLA; HECTD3; PIK3AP1; CTSC; MYO1C; BTR02; RNF144B

    asb11 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by asb11 itself. We selected most functions asb11 had, and list some proteins which have the same functions with asb11. You can find most of the proteins on our site.

    Function Related Protein
    molecular_function IMMP1L; HIST1H2BQ; PHLDB2; TMEM57A; LMBRD2B; SPRYD4; INO80C; NHLRC4; FAM69C; FAM100B

    asb11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with asb11 here. Most of them are supplied by our site. Hope this information will be useful for your research of asb11.

    Fingert, JH; Roos, BR; et al. Analysis of ASB10 variants in open angle glaucoma. HUMAN MOLECULAR GENETICS 21:4543-4548(2012).
    da Silva, MAS; Tee, JM; et al. Essential Role for the d-Asb11 cul5 Box Domain for Proper Notch Signaling and Neural Cell Fate Decisions In Vivo. PLOS ONE 5:-(2010).

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