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Recombinant Human ASB11 protein, GST-tagged

Cat.No. : ASB11-884H
Product Overview : Human ASB11 full-length ORF ( NP_543149.1, 1 a.a. - 323 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 61.8 kDa
AA Sequence : MEDGPVFYGFKNIFITMFATFFFFK LLIKVFLALLTHFYIVKGNRKEAAR IAEEIYGGISDCWADRSPLHEAAAQ GRLLALKTLIAQGVNVNLVTINRVS SLHEACLGGHVACAKALLENGAHVN GVTVHGATPLFNACCSGSAACVNVL LEFGAKAQLEVHLASPIHEAVKRGH RECMEILLANNVNIDHEVPQLGTPL YVACTYQRVDCVKKLLELGASVDHG QWLDTPLHAAARQSNVEVIHLLTDY GANLKRRNAQGKSALDLAAPKSSVE QALLLREGPPALSQLCRLCVRKCLG RACHQAIHKLHLPEPLERFLLYQ
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ASB11 ankyrin repeat and SOCS box containing 11 [ Homo sapiens ]
Official Symbol : ASB11
Synonyms : ASB11; ankyrin repeat and SOCS box containing 11; ankyrin repeat and SOCS box protein 11; DKFZp779E2460; ASB-11; ankyrin repeat domain-containing SOCS box protein ASB11; MGC119168; MGC119169;
Gene ID : 140456
mRNA Refseq : NM_001012428
Protein Refseq : NP_001012428
MIM : 300626
UniProt ID : Q8WXH4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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Does ASB11 have RNA-binding properties? 04/25/2023

ASB11 does not possess known RNA-binding domains or motifs, and its functions primarily revolve around protein degradation mechanisms.

Does ASB11 have a role in neural development? 04/18/2023

The involvement of ASB11 in neural development is not extensively studied, and further research is needed to determine if it plays a role in this process.

Is ASB11 associated with synaptic plasticity? 12/08/2022

The specific association of ASB11 with synaptic plasticity remains unknown, and more research is required to elucidate its potential role in modulating this process.

Does ASB11 interact with other proteins? 06/18/2022

Yes, ASB11 can interact with different protein substrates, facilitating their ubiquitination and subsequent degradation through the ubiquitin-proteasome system.

Can ASB11 influence cell growth and proliferation? 05/15/2019

ASB11's association with protein degradation pathways implies its potential role in regulating cell growth and proliferation, although specific mechanisms are still being investigated.

Is ASB11 involved in cellular signaling pathways? 07/05/2018

ASB11's SOCS box domain suggests its possible involvement in modulating cellular signaling by targeting specific proteins for degradation.

Can ASB11 regulate protein turnover and stability? 02/09/2017

Yes, ASB11 is believed to have a role in regulating protein turnover and stability through its ability to target proteins for degradation via the ubiquitin-proteasome system.

Customer Reviews (3)

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Reviews
04/16/2023

    the ASB11 protein's exceptional qualities, combined with the manufacturer's comprehensive technical support, make it an ideal choice for researchers seeking reliable experimental materials and reliable assistance in their scientific endeavors.

    03/20/2017

      Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.

      08/31/2016

        Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.

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