Recombinant Human ASB11 protein, GST-tagged
Cat.No. : | ASB11-884H |
Product Overview : | Human ASB11 full-length ORF ( NP_543149.1, 1 a.a. - 323 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 61.8 kDa |
AA Sequence : | MEDGPVFYGFKNIFITMFATFFFFK LLIKVFLALLTHFYIVKGNRKEAAR IAEEIYGGISDCWADRSPLHEAAAQ GRLLALKTLIAQGVNVNLVTINRVS SLHEACLGGHVACAKALLENGAHVN GVTVHGATPLFNACCSGSAACVNVL LEFGAKAQLEVHLASPIHEAVKRGH RECMEILLANNVNIDHEVPQLGTPL YVACTYQRVDCVKKLLELGASVDHG QWLDTPLHAAARQSNVEVIHLLTDY GANLKRRNAQGKSALDLAAPKSSVE QALLLREGPPALSQLCRLCVRKCLG RACHQAIHKLHLPEPLERFLLYQ |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ASB11 ankyrin repeat and SOCS box containing 11 [ Homo sapiens ] |
Official Symbol : | ASB11 |
Synonyms : | ASB11; ankyrin repeat and SOCS box containing 11; ankyrin repeat and SOCS box protein 11; DKFZp779E2460; ASB-11; ankyrin repeat domain-containing SOCS box protein ASB11; MGC119168; MGC119169; |
Gene ID : | 140456 |
mRNA Refseq : | NM_001012428 |
Protein Refseq : | NP_001012428 |
MIM : | 300626 |
UniProt ID : | Q8WXH4 |
Products Types
◆ Recombinant Protein | ||
ASB11-774M | Recombinant Mouse ASB11 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASB11-251R | Recombinant Rhesus Macaque ASB11 Protein, His (Fc)-Avi-tagged | +Inquiry |
ASB11-01H | Recombinant Human ASB11 Protein, His-tagged | +Inquiry |
ASB11-2007M | Recombinant Mouse ASB11 Protein | +Inquiry |
ASB11-422R | Recombinant Rhesus monkey ASB11 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (7)
Ask a questionASB11 does not possess known RNA-binding domains or motifs, and its functions primarily revolve around protein degradation mechanisms.
The involvement of ASB11 in neural development is not extensively studied, and further research is needed to determine if it plays a role in this process.
The specific association of ASB11 with synaptic plasticity remains unknown, and more research is required to elucidate its potential role in modulating this process.
Yes, ASB11 can interact with different protein substrates, facilitating their ubiquitination and subsequent degradation through the ubiquitin-proteasome system.
ASB11's association with protein degradation pathways implies its potential role in regulating cell growth and proliferation, although specific mechanisms are still being investigated.
ASB11's SOCS box domain suggests its possible involvement in modulating cellular signaling by targeting specific proteins for degradation.
Yes, ASB11 is believed to have a role in regulating protein turnover and stability through its ability to target proteins for degradation via the ubiquitin-proteasome system.
Customer Reviews (3)
Write a reviewthe ASB11 protein's exceptional qualities, combined with the manufacturer's comprehensive technical support, make it an ideal choice for researchers seeking reliable experimental materials and reliable assistance in their scientific endeavors.
Its excellent performance in ELISA assays makes it a valuable tool in quantifying analytes in biological samples.
Its reliability, specificity, and versatility make it an invaluable asset in studying and understanding complex biological systems.
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