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Official Full Name ATPase, Na+/K+ transporting, beta 4 polypeptide
Background This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms ATP1B4; ATPase, Na+/K+ transporting, beta 4 polypeptide; ATPase, (Na+)/K+ transporting, beta 4 polypeptide; protein ATP1B4; X,K-ATPase beta-m subunit; x/potassium-transporting ATPase subunit beta-m
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • T7
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP1B4-2941H Recombinant Human ATP1B4 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ATP1B4-3984H Recombinant Human ATP1B4 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ATP1B4-48HCL Recombinant Human ATP1B4 lysate HEK293 N/A
    Human ATP1B4-968H Recombinant Human ATP1B4 protein Wheat Germ N/A
    Mouse Atp1b4-1765M Recombinant Mouse Atp1b4 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Mouse ATP1B4-2119M Recombinant Mouse ATP1B4 Protein Mammalian Cell His
    Rat ATP1B4-1535R Recombinant Rat ATP1B4 protein, His & T7-tagged E.coli His/T7
    Rat ATP1B4-858R Recombinant Rat ATP1B4 Protein Mammalian Cell His
    Chicken ATP1B4-3443C Recombinant Chicken ATP1B4 Mammalian Cell His

    atp1b4 involved in several pathways and played different roles in them. We selected most pathways atp1b4 participated on our site, such as cGMP-PKG signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with atp1b4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    cGMP-PKG signaling pathway PRKG1; PIK3CD; MEF2D; OPRD1; PLCB3; GTF2IRD1; PDE5A; FXYD2; PLCB1; SLC8A2
    cAMP signaling pathway HTR4; CAMK4; NFKBIA; MAPK10; GNAS; PTGER3; PIK3R2; HCAR2; CAMK2B; VAV1
    Cardiac muscle contraction COX5B; COX6A1; ATP1A3B; COX6B1; ATP1A3; MYH15; MYH7; ATP1A2; ATP1A1; ATP1B2A
    Adrenergic signaling in cardiomyocytes RPS6KA5; CACNB2; CREB3L3A; CACNG6; CACNB2A; AKT2L; PPP1R1A; GNAI3; ATF4; TNNC1
    Insulin secretion RIMS2; PLCB4; FFAR1; PDX1; GNA11; KCNMA1; FXYD2; RAPGEF4; CREB3L2; CREB5
    Thyroid hormone synthesis ATP1A1; TSHB; DUOX2; CREB3L2; GPX7; ASGR1; GPX3; ATF4; CREB3L1; ITPR3
    Thyroid hormone signaling pathway MDM2; SLC2A1; PIK3CG; TBC1D4; KAT2A; THRB; KAT2B; EP300; PIK3R5; TSC2
    Aldosterone-regulated sodium reabsorption PIK3R1; SGK1; MAPK1; PRKCB; IGF1; PIK3R5; IRS1; SCNN1G; NR3C2; PIK3CA
    Endocrine and other factor-regulated calcium reabsorption PRKACG; ESR1; ATP1B2; BDKRB2; ATP1B1; ATP1A2; KLK1B24; ATP1B4; GNAS; KLK2
    Proximal tubule bicarbonate reclamation Car4; GLS2; CA2; SLC9A3; SLC25A10; ATP1B4; PCK2; CA4; ATP1A1; GLUD2
    Salivary secretion PLCB1; PRKG2; LYZ2; PLCB2; CD38; CALM1; MUC5B; BST1; DMBT1; LYZ1
    Gastric acid secretion PRKACB; MYLK3; KCNK2; KCNJ16; ACTB; PRKCB; MYLK2; ATP4A; ATP1B1; KCNJ2
    Pancreatic secretion RAB3D; ATP2B4; PLCB4; ATP1B1; CLCA5; CPB2; ATP1B2; CELA3A; PNLIPRP2; Slc4a2
    Carbohydrate digestion and absorption SI; Amy1; AMY2A4; PIK3R2; AKT1; AKT2; TAS1R2; HK2; AMY1B; SLC37A4
    Protein digestion and absorption CPA2; SLC16A10; COL6A5; KCNE3; CELA3B; SLC38A2; SLC15A1; COL4A1; SLC7A8; ATP1B4
    Bile secretion OSTA; SLC10A1; SLC9A1; SLC27A5; CYP3A4; PRKACB; AQP8; ADCY9; ADCY7; OSTB
    Mineral absorption ATP1A1; ATP2B1; TF; MT2; SLC31A1; FXYD2; CLCN2; SLC40A1; ATP1B2; MT1X

    atp1b4 has several biochemical functions, for example, monovalent inorganic cation transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by atp1b4 itself. We selected most functions atp1b4 had, and list some proteins which have the same functions with atp1b4. You can find most of the proteins on our site.

    Function Related Protein
    monovalent inorganic cation transmembrane transporter activity ATP1B4

    atp1b4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with atp1b4 here. Most of them are supplied by our site. Hope this information will be useful for your research of atp1b4.

    Gao, K; Song, Z; et al. Genetic analysis of the ATP1B4 gene in Chinese Han patients with Parkinson's disease. MOLECULAR BIOLOGY REPORTS 41:2307-2311(2014).
    Sarkozy, M; Zvara, A; et al. Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats. CARDIOVASCULAR DIABETOLOGY 12:-(2013).

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