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Official Full Name ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Background This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14.
Synonyms ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; ATP5C, ATP5CL1; ATP synthase subunit gamma, mitochondrial; ATP synthase gamma chain, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma subunit; ATP5C 1; ATP5C; ATP5CL1; F ATPase gamma subunit; Mitochondrial ATP synthase, gamma subunit 1; F-ATPase gamma subunit
    • Species :
    • Bovine
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ATP5C1-10016H Recombinant Human ATP5C1, GST-tagged E.coli GST
    Human ATP5C1-132H Recombinant Human ATP5C1Protein, His-tagged E.coli His
    Human ATP5C1-133H Recombinant Human ATP5C1 Protein, His-tagged E.coli His
    Human ATP5C1-7626H Recombinant Human ATP5C1, His-tagged E.coli N/A
    Human ATP5C1-8603HCL Recombinant Human ATP5C1 293 Cell Lysate HEK293 N/A
    Human ATP5C1-8604HCL Recombinant Human ATP5C1 293 Cell Lysate HEK293 N/A
    Human ATP5C1-978H Recombinant Human ATP5C1 protein, GST-tagged Wheat Germ GST
    Rat Atp5c1-3722R Recombinant Rat Atp5c1, His-tagged E.Coli or Yeast His
    Cynomolgus Monkey ATP5C1-322C Recombinant Cynomolgus ATP5C1 Protein, His-tagged Mammalian Cell His
    Bovine ATP5C1-3723B Recombinant Bovine ATP5C1, His-tagged E.Coli or Yeast His
    Chicken ATP5C1-5361C Recombinant Chicken ATP5C1 Mammalian Cell His
    Zebrafish ATP5C1-10396Z Recombinant Zebrafish ATP5C1 Mammalian Cell His

    atp5c1 involved in several pathways and played different roles in them. We selected most pathways atp5c1 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with atp5c1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Oxidative phosphorylation COX11; ATP6V0E2; UQCRFS1; MT-ND4; ATP6V1E1; ATP5G3B; NDUFA7; NDUFS6; LHPP; ATP6V1D
    Metabolic pathways ALG9; POLR3G; NDUFA7; MTHFD1; NFS1; GCSHA; EXT1B; NME5; DOLK; POLA2
    Alzheimers disease NDUFA11; MAPK1; RYR3; NDUFV1; GSK3B; ATP5B; NDUFA13; ATP5A1; NDUFV3; CALM1
    Parkinsons disease NDUFB8; COX8C; PARK7; ATP5H; COX7B; SLC18A1; NDUFB6; NDUFA8; COX6B2; NDUFA5
    Huntingtons disease GPX1; GRIN1; PLCB4; POLR2J2; DNAH11; PLCB3; DNAI1; HIP1; NDUFA12; SDHC

    atp5c1 has several biochemical functions, for example, contributes_to ATPase activity, poly(A) RNA binding, proton-transporting ATP synthase activity, rotational mechanism. Some of the functions are cooperated with other proteins, some of the functions could acted by atp5c1 itself. We selected most functions atp5c1 had, and list some proteins which have the same functions with atp5c1. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to ATPase activity ATP5F1; ATP1B1; PPP2R4; ATP5L; ATP5E; ATP5I; ATP1A2; ATP5B; ATP5D; ATP5A1
    poly(A) RNA binding PSMC1; HNRNPAB; GFM1; RPL23; EIF1AX; DIEXF; CDK13; UBE2N; MRPL37; PCBP1
    proton-transporting ATP synthase activity, rotational mechanism ATP5O; ATP6AP1; ATP6V0C; ATP6AP1B; ATP5B; ATP5A1; ATP5E; ATP5C1
    proton-transporting ATPase activity, rotational mechanism ATP6V1AA; ATP6V0A4; ATP6V1E2; ATP6V1A; ATP6V0A1; ATP6V0A1A; TCIRG1; ATP6V0E2; ATP6V1F; ATP6V1C1
    transmembrane transporter activity SLC2A11B; SLC2A8; ATP5C1; SLC2A11L; ATP5I; SLCO1D1; ATP5H; ATP5D; SLC22A16; SLC22A7A

    atp5c1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with atp5c1 here. Most of them are supplied by our site. Hope this information will be useful for your research of atp5c1.


    Ding, BQ; Xi, Y; et al. Gene Expression Profiles of Entorhinal Cortex in Alzheimer's Disease. AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS 29:526-532(2014).
    MacLeod, G; Varmuza, S; et al. Tandem Affinity Purification in Transgenic Mouse Embryonic Stem Cells Identifies DDOST as a Novel PPP1CC2 Interacting Protein. BIOCHEMISTRY 51:9678-9688(2012).

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