ATP5C1
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Official Full Name
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
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Overview
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. -
Synonyms
ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; ATP5C, ATP5CL1; ATP synthase subunit gamma, mitochondrial; ATP synthase gamma chain, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma subunit; ATP5C 1; ATP5C; ATP5CL1; F ATPase gamma subunit; Mitochondrial ATP synthase, gamma subunit 1; F-ATPase gamma subunit;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bovine
- Chicken
- Cynomolgus Monkey
- Human
- Rat
- Zebrafish
- E.coli
- E.Coli or Yeast
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Myc
- Non
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | ATP5C1-10016H | Recombinant Human ATP5C1, GST-tagged | E.coli | GST | 1-298a.a. | |
Human | ATP5C1-978H | Recombinant Human ATP5C1 protein, GST-tagged | Wheat Germ | GST | ||
Human | ATP5C1-133H | Recombinant Human ATP5C1 Protein, His-tagged | E.coli | His | ||
Human | ATP5C1-132H | Recombinant Human ATP5C1Protein, His-tagged | E.coli | His | ||
Human | ATP5C1-7626H | Recombinant Human ATP5C1, His-tagged | E.coli | Non | 26-298aa | |
Human | ATP5C1-8603HCL | Recombinant Human ATP5C1 293 Cell Lysate | HEK293 | Non | ||
Human | ATP5C1-8604HCL | Recombinant Human ATP5C1 293 Cell Lysate | HEK293 | Non | ||
Human | ATP5C1-1388HF | Recombinant Full Length Human ATP5C1 Protein, GST-tagged | In Vitro Cell Free System | GST | 298 amino acids | |
Human | ATP5C1-1175H | Recombinant Human ATP5C1 protein, His&Myc-tagged | E.coli | His&Myc | 26-298aa | |
Rat | Atp5c1-3722R | Recombinant Rat Atp5c1, His-tagged | E.Coli or Yeast | His | 273 | |
Bovine | ATP5C1-3723B | Recombinant Bovine ATP5C1, His-tagged | E.Coli or Yeast | His | 298 | |
Cynomolgus Monkey | ATP5C1-322C | Recombinant Cynomolgus ATP5C1 Protein, His-tagged | Mammalian Cell | His | ||
Cynomolgus Monkey | ATP5C1-72C | Recombinant Cynomolgus Monkey ATP5C1 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi | ||
Cynomolgus Monkey | ATP5C1-72C-B | Recombinant Cynomolgus Monkey ATP5C1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | ATP5C1-10396Z | Recombinant Zebrafish ATP5C1 | Mammalian Cell | His | ||
Chicken | ATP5C1-5361C | Recombinant Chicken ATP5C1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- Other Resource
ATP5C1 involved in several pathways and played different roles in them. We selected most pathways ATP5C1 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Alzheimers disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP5C1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Oxidative phosphorylation | ATP5H;ATP6V0A1;ATP6V1G1;COX5AA;NDUFA3;COX4I2;SDHC;ATP5B;NDUFA11 |
Metabolic pathways | CYP2C50;PHOSPHO2;PNPO;GATM;TPI1;HYKK.2;DPM2;Cel;AGXT2L2 |
Alzheimers disease | PLCB4;ATP5B;NDUFA4L2;APH1C;GSK3B;ATP2A1;SNCA;NDUFB10;MAPK3 |
Parkinsons disease | NDUFS5;NDUFS4;NDUFA2;GNAI2;UQCRB;COX6A2;COX6B2;UCHL1;NDUFV3 |
Huntingtons disease | ATP5E;mt-Atp8;COX8C;POLR2J3;NDUFB8;NDUFB11;SOD2;DNAH6;DNAI2 |
ATP5C1 has several biochemical functions, for example, contributes_to ATPase activity, poly(A) RNA binding, proton-transporting ATP synthase activity, rotational mechanism. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP5C1 itself. We selected most functions ATP5C1 had, and list some proteins which have the same functions with ATP5C1. You can find most of the proteins on our site.
Function | Related Protein |
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contributes_to ATPase activity | ATP5B;ATP5H;MSH2;SFRP5;ATP5D;ATP5O;ABCG8;ATP5E;ATP5L |
poly(A) RNA binding | EIF3D;STRAP;SLC25A5;FNDC3B;PEBP1;PPAN;HSPA9;TARDBP;MYBBP1A |
proton-transporting ATP synthase activity, rotational mechanism | ATP6AP1;ATP5C1;ATP6V0C;ATP5E;ATP6AP1B;ATP5B;ATP5O;ATP5A1 |
proton-transporting ATPase activity, rotational mechanism | ATP6V1E2;ATP6V1B2;ATP6AP1B;ATP6V0A4;ATP6V1C1;ATP6AP1;ATP6V0A2B;ATP5A1;ATP6V0A2 |
transmembrane transporter activity | SLC2A15B;ATP5B;ATP5F1;SLC22A16;SLC2A11B;SLC22A20;SLC2A1A;SLC2A15A;SLC17A9 |
ATP5C1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP5C1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP5C1.
MYC; VCAM1; P; ATF2; ATP5F1; CA12; NDUFB3; EGFR; SERPINA1; ITIH2; PTN; CCND3; ELOF1
Research Area
Related articles
- Reviews
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Customer Reviews (3)
Write a reviewThe exceptional stability of this protein makes it an invaluable tool for a wide range of applications.
Due to the wide application of proteins, researchers can conduct research in more fields and broaden the horizon of scientific research.
Because the extraordinary activity of proteins makes them valuable tools for a wide range of applications.
Q&As (6)
Ask a questionATP5C1 expression and function are affected by a variety of regulatory mechanisms, including regulation of transcription factors and epigenetic modifications.
Yes, ATP5C1 expression levels may be associated with the development and progression of certain diseases.
ATP5C1 is highly expressed in multiple tissues and organs, especially metabolically active tissues such as heart, liver, and brain.
Yes, ATP5C1 gene mutations are associated with certain neurological diseases such as Parkinson's disease, cerebral ischemia, etc.
It may play a role in tumor cell metabolism and energy supply.
ATP5C1 protein may be related to the occurrence and progression of metabolic diseases such as obesity and diabetes.
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