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ATP6V1C2

Official Full Name

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
Background

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. This gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
Synonyms

ATP6V1C2; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; ATPase, H+ transporting, lysosomal 42kD, V1 subunit C isoform 2 , ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C isoform 2; V-type proton ATPase subunit C 2; ATP6C2; VMA5; ATPase H+ transporting lysosomal 42kDa V1 subunit C2; V ATPase C2 subunit; V ATPase subunit C 2; V type proton ATPase subunit C 2; V-ATPase subunit C 2; Vacuolar ATP synthase subunit C 2; Vacuolar H+ ATPase C2; Vacuolar proton pump subunit C 2; VATC2_HUMAN; VMA 5; OTTHUMP00000115522; OTTHUMP00000200400; V-ATPase C2 subunit;

Type:
Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species :
Human
Mouse
Rat

Source :
E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag :
GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	ATP6V1C2-8581HCL	Recombinant Human ATP6V1C2 293 Cell Lysate	HEK293	N/A	Inquiry
Human	ATP6V1C2-279H	Recombinant Human ATP6V1C2 Protein, His-tagged	E.coli	His	Inquiry
Human	ATP6V1C2-1004H	Recombinant Human ATP6V1C2 protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	ATP6V1C2-10044H	Recombinant Human ATP6V1C2, GST-tagged	E.coli	GST	$319.00 / 25ug
Mouse	ATP6V1C2-2162M	Recombinant Mouse ATP6V1C2 Protein	Mammalian Cell	His	Inquiry
Mouse	ATP6V1C2-878M	Recombinant Mouse ATP6V1C2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug
Mouse	ATP6V1C2-878M-B	Recombinant Mouse ATP6V1C2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	ATP6V1C2-548R-B	Recombinant Rat ATP6V1C2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	ATP6V1C2-892R	Recombinant Rat ATP6V1C2 Protein	Mammalian Cell	His	Inquiry
Rat	ATP6V1C2-548R	Recombinant Rat ATP6V1C2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	$2,998.00 / 50ug

Involved Pathway
Protein Function
Interacting Protein
ATP6V1C2 Related Articles

ATP6V1C2 involved in several pathways and played different roles in them. We selected most pathways ATP6V1C2 participated on our site, such as Oxidative phosphorylation, Metabolic pathways, Phagosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with ATP6V1C2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Oxidative phosphorylation	NDUFC2;ATPV0E2;ATP6V0D2;ATP5C1;ATP6V1F;COX5B2;ATP5D;NDUFA10;ATP6V1B1
Metabolic pathways	RIMKLB;LIPCA;ACSM2B;HIBADH;GALNT11;MDH1AA;UQCRH;HK1;P4HA1A
Phagosome	TLR2-1;TUBAL3;TLR4;HLA-A;HLA-DRA;ATP6V1H;SEC61G;HLA-DMA;ATP6V1G1
Synaptic vesicle cycle	STX3;CPLX2;SNAP25;SLC17A8;VAMP2;SLC17A6;ATP6V0D1;STX1B;ATP6V0A1
Collecting duct acid secretion	ATP6V0A1;ATP6V0D1;ATP6V1A;ATP6V0C;ATP6V0E2;ATP4A;ATP6V1E1;ATP6V1B1;SLC4A1
Vibrio cholerae infection	ATP6V0C;ATP6V1B1;KDELR1;PRKCA;ATP6V1E1;MUC2;ATP6V1B2;PRKACG;ATP6V0B
Epithelial cell signaling in Helicobacter pylori infection	MAP2K4;ATP6V1H;MAPK8;ATP6V1G2;ATP6V1G3;ATP6V1B1;RAC1;MAPK13;JAM3
Rheumatoid arthritis	HLA-DQA2;FOS;ATP6V1A;HLA-DMB;ATP6V1C1;IL15;TGFB2;ATP6V0A1;ATP6V0E2

ATP6V1C2 has several biochemical functions, for example, hydrogen-exporting ATPase activity, phosphorylative mechanism, protein binding, protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ATP6V1C2 itself. We selected most functions ATP6V1C2 had, and list some proteins which have the same functions with ATP6V1C2. You can find most of the proteins on our site.

Function	Related Protein
hydrogen-exporting ATPase activity, phosphorylative mechanism	ATP6V1C1;ATP6V1E1;ATP6V0D1;ATP6V1G3;ATP6V1C2;ATP6V1G1;ATP6V1E2
protein binding	SDC4;FPR1;BSG;RGS1;TTC5;SERTAD1;GM5506;CLUAP1;ZNHIT6
protein dimerization activity	NPAS4A;HER4.3;MITFA;POLR2J;MESPAB;NEUROD6A;TAL2;PTF1A;ID2B

ATP6V1C2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ATP6V1C2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ATP6V1C2.

GOLGA2; q81l81_bacan; pi3p; ATP6V1G1; ATP6V1B2; ATP6V1A; MAGEA6; MRPS9; TTC9C; ECSIT

Ropka-Molik, K; Zukowski, K; et al. Comprehensive analysis of the whole transcriptomes from two different pig breeds using RNA-Seq method. ANIMAL GENETICS 45:674-684(2014).

Kandil, OM; Ghanem, N; et al. Transcriptional Analysis of Buffalo (Bubalus bubalis) Oocytes During In Vitro Maturation Using Bovine cDNA Microarray. REPRODUCTION IN DOMESTIC ANIMALS 45:63-74(2010).