Recombinant Human ATP6V1C2 Protein, His-tagged

• Cat.No.: ATP6V1C2-279H
• Product Overview: Recombinant Human ATP6V1C2, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: THis gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A,three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. THis gene encodes alternate transcriptional splice variants, encoding different V1 domain C subunit isoforms.
• Source: E. coli
• Tag: His
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigradeentigradeentigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 48.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 [ Homo sapiens ]
• Official Symbol: ATP6V1C2
• Synonyms: ATP6V1C2; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; ATPase, H+ transporting, lysosomal 42kD, V1 subunit C isoform 2 , ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C isoform 2; V-type proton ATPase subunit C 2; ATP6C2; VMA5; V-ATPase C2 subunit; V-ATPase subunit C 2; vacuolar proton pump subunit C 2
• Gene ID: 245973
• mRNA Refseq: NM_001039362
• Protein Refseq: NP_001034451
• UniProt ID: Q8NEY4