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B3GNT3

Official Full Name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Overview

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
Synonyms

B3GNT3; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3; TMEM3; B3GN T3; B3GNT 3; beta 1; 3 N acetylglucosaminyltransferase bGnT 3; beta3Gn T3; HP10328; putative type II membrane protein; transmembrane protein 3; B3GAL T8; B3GALT8; Beta 1,3 galactosyltransferase 8; Beta 3 Gal T8; Beta3Gal T8; Beta3GalT8; BGnT 3; BGnT3; Core 1 extending beta 1,3 N acetylglucosaminyltransferase; Core1 beta3GlcNAcT; UDP Gal:beta GlcNAc beta 1,3 galactosyltransferase 8; UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 3; beta-3-Gx-T8; beta-1,3-Gn-T3; beta-1,3-GalTase 8; core1-beta3GlcNAcT; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; core 1 extending beta-1,3-N-acetylglucosaminyltransferase; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8; B3GN-T3; B3GNT-3; B3GAL-T8; beta3Gn-T3;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	B3GNT3-020H	Recombinant Human B3GNT3 protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	B3GNT3-10104H	Recombinant Human B3GNT3, His-tagged	E.coli	His	34-372a.a.	$319 / 25ug
Human	B3GNT3-021H	Recombinant Human B3GNT3 protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	B3GNT3-8543HCL	Recombinant Human B3GNT3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	B3GNT3-1633HF	Recombinant Full Length Human B3GNT3 Protein, GST-tagged	In Vitro Cell Free System	GST	372 amino acids	Inquiry
Human	B3GNT3-291H	Recombinant Human B3GNT3 Protein, His-tagged	E.coli	N-His	Leu165-Arg277	Inquiry
Mouse	B3GNT3-2241M	Recombinant Mouse B3GNT3 Protein	Mammalian Cell	His		Inquiry
Mouse	B3GNT3-930M	Recombinant Mouse B3GNT3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	B3GNT3-930M-B	Recombinant Mouse B3GNT3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	B3GNT3-6108Z	Recombinant Zebrafish B3GNT3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

B3GNT3 involved in several pathways and played different roles in them. We selected most pathways B3GNT3 participated on our site, such as Glycosaminoglycan metabolism, Glycosphingolipid biosynthesis - lacto and neolacto series, Keratan sulfate biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with B3GNT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Glycosaminoglycan metabolism	VCANB;CHP;B3GAT2;CHST9;B3GNT3;HAS3;CSPG5B;STAB2;PRELP
Glycosphingolipid biosynthesis - lacto and neolacto series	ST3GAL3B;FUT9A;FUT6;FUT4;B3GNTL2;GCNT2;ST3GAL6;B3GALT1;B4GALT2
Keratan sulfate biosynthesis	B3GNT2A;OMD;SLC35D2;ST3GAL3A;PRELP;FMODA;B3GNT1;B3GNT2;OGN
Keratan sulfate/keratin metabolism	FMODA;B3GNT3;SLC35D2;ST3GAL3A;B3GNT2;B3GNT1;B3GNT2A;GLB1L;OMD
Metabolic pathways	CYP8B1;AANAT;PAFAH1B2;CYP2J6;HMGCRB;PNPLA3;PCYT1AB;HPD;UQCRB
Metabolism	APOA4B.2;CTHL;KCNS3;ATP5S;CES1;PLB1;NAGS;AGPAT6;COX16
Metabolism of carbohydrates	SLC5A2;OXSR1;SLC5A9;B3GNT2;SLC35B2;HS3ST6;B3GNT2A;HPSE;SLC5A4
Metabolism of proteins	WDR85;YIF1A;SFTPB;TIMM8A;MUC1;SAE1;MGAT4B;DPP4;ADAMTSL5

B3GNT3 has several biochemical functions, for example, N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity, beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity, galactosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by B3GNT3 itself. We selected most functions B3GNT3 had, and list some proteins which have the same functions with B3GNT3. You can find most of the proteins on our site.

Function	Related Protein
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	B3GNT3;GCNT2;B3GNT2;B3GNT4;B3GNT1
beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	B3GNT6;B3GNT3;POMGNT1
galactosyltransferase activity	GALNTL4;B3GNT3;DPY19L4;B3GNT2A;B4GALT4;B3GNT2;B3GNTL1;GTDC2;B4GALT1

B3GNT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with B3GNT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of B3GNT3.