|Official Full Name||BTB and CNC homology 1, basic leucine zipper transcription factor 1|
|Background||This gene encodes a transcription factor that belongs to the capncollar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.|
|Synonyms||BACH1; BTB and CNC homology 1, basic leucine zipper transcription factor 1; transcription regulator protein BACH1; BACH 1; HA2303; BTB and CNC homolog 1; basic region leucine zipper transcriptional regulator BACH1; BACH-1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
bach1 involved in several pathways and played different roles in them. We selected most pathways bach1 participated on our site, such as Integrated Breast Cancer Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with bach1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Integrated Breast Cancer Pathway||PLK3; JAKMIP1; DAG1; SELK; BACH1; EDAR; C21orf7; NOXA1; USP38; CYP19A1|
bach1 has several biochemical functions, for example, RNA polymerase II distal enhancer sequence-specific DNA binding, heme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by bach1 itself. We selected most functions bach1 had, and list some proteins which have the same functions with bach1. You can find most of the proteins on our site.
|RNA polymerase II distal enhancer sequence-specific DNA binding||CDX2; NR5A2; NR1H4; MIXL1; H2AFZ; RELA; MED12; GATA2; TFAP2C; SFPQ|
|heme binding||CYP51A1; CYP2X9; IRGM1; CYP4X1; CYP2C70; CYP2K16; IDO1; CYP8B3; CYP4F3; HBZ|
|protein binding||GRIK5; TMEM8B; SERPINA3; ASGR2; LAMTOR1; CSF3R; TMEM100; DGKZ; NME3; RABEP1|
|transcription factor activity, sequence-specific DNA binding||RFX8; POUV; GCM1; CITED2; NFE2L1B; ZFP110; AFF4; ZNF193; ATF7; ZNF202|
|transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding||SIX6; ARID3B; SUB1; MEOX2; CUX1; NFE2L1; BACH1; NFE2L2; RELA; NFATC1|
|transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding||NR2C1; PROX1A; ZFP90; NFIL3-6; CREBBP; ZFPM2A; NEUROG3; SPI1; NKX6-2; TGIF1|
|transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding||PROP1; GZF1; BACH1; PAX4; MSC; ZBTB16; ARX; BACH2|
|contributes_to ubiquitin-protein transferase activity||KLHL24B; BACH2; KLHL20; BCOR; BACH1A; KLHL2; TCEB3C; IPP; FBXL15; KLHL10|
bach1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with bach1 here. Most of them are supplied by our site. Hope this information will be useful for your research of bach1.
MAFG; MAF; FOS; ATF2; CREB1; ATF7; ATF1; DDIT3; BATF; meq_gahvm; MAFB; Bach1; ANAPC5; h0y2u5_human; TMEM208