Ccl21a
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Official Full Name
chemokine (C-C motif) ligand 21A (serine) -
Overview
Chemokine (C-C motif) ligand 21 (CCL21) is a small cytokine belonging to the CC chemokine family. This chemokine is also known as 6Ckine (because it has six conserved cysteine residues instead of the four cysteines typical to chemokines), exodus-2, and secondary lymphoid-tissue chemokine (SLC). The gene for CCL21 is located on human chromosome 9. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7. -
Synonyms
Ccl21a;chemokine (C-C motif) ligand 21A (serine);ALP;SLC;plt;CKb9;Tca4;6Ckine;Scya21;6CKBAC2;SCYA21a;Scya21b;AW987545
Recombinant Proteins
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- Insect Cells
- Non
- His
- Avi
- Fc
Involved Pathway
Ccl21a involved in several pathways and played different roles in them. We selected most pathways Ccl21a participated on our site, such as Cytokine-cytokine receptor interaction,Chemokine signaling pathway,NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ccl21a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | CXCR3,IL20RA,XCL2,CSF2RA,MET,IL3,PF4V1,KIT,LTBR,IL7R |
| NF-kappa B signaling pathway | TNFRSF1A,VCAM1,CD14,GADD45B,Bcl2a1b,TLR4,ERC1,LAT,TNFAIP3,CD40LG |
| Chemokine signaling pathway | GM10591,PF4V1,PARD3,XCR1,GSK3B,IL-8,CXCR2,CCL6,CXCL5,CCL25 |
Protein Function
Ccl21a has several biochemical functions, for example, chemokine activity,chemokine receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ccl21a itself. We selected most functions Ccl21a had, and list some proteins which have the same functions with Ccl21a. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chemokine activity | CCL21B,IL8L2,CXCL13,CCL39.1,CCL25B,CCL33.2,CXCL3,CXCL5,CCL33.3,CCL28 |
| chemokine receptor binding | CCL25,Ccl21c,CCL19,CCRL2,CCL5,S100A14,CCL21B,XCL1,CXCL12,CCL21 |
Interacting Protein
Ccl21a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ccl21a here. Most of them are supplied by our site. Hope this information will be useful for your research of Ccl21a.
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