Active Recombinant Mouse Chemokine (C-C motif) Ligand 21A (serine) Ccl21a-412M

Active Recombinant Mouse Chemokine (C-C motif) Ligand 21A (serine)


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Active Recombinant Mouse Chemokine (C-C motif) Ligand 21A (serine)

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Cat.No. : Ccl21a-412M Optional Service: Optional requirements on this protein
Product Overview : Recombinantmouse Ccl21a protein was expressed in E. coli. Ser24-Gly133.
Description : Mouse Ccl21a cDNAencodes a 133 amino acid residue protein with a 23 residue signal peptide thatis cleaved to generate the 110 residue mature protein. Human and mouse Ccl21aare highly conserved, exhibiting 86% amino acid sequence identity. Ccl21a isconstitutively expressed at high levels in lymphoid tissues such as lymphnodes, spleen and appendix.
Source : E. coli
Form : Lyophilized from a0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrierprotein.
N-terminal Sequence : Ser24
Molecular Weight : 12 kDa
Activity : Measured by itsability to chemoattract 5-10 day cultured human peripheral blood lymphocytes(PBL). The ED50 for this effect is typically 50-200 ng/mL. Measuredby its ability to chemoattract human CCR7 transfected BaF3 mouse pro-B cells.The ED50 for this effect is typically 3-15 ng/mL.
Endotoxin Level : <1.0 EU per 1 μgof the protein by the LAL method.
Purity : >97%,by SDS-PAGE under reducing conditions and visualized by silver stain.
Reconstitution : Reconstitute at 10μg/mL in sterile PBS that containing at least 0.1% human or bovine serumalbumin.
Storage : Use amanual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month,2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions afterreconstitution.
Gene Name : Ccl21a chemokine (C-C motif)ligand 21A (serine) [ Mus musculus ]
Official Symbol : Ccl21a
Synonyms : Ccl21a;chemokine (C-C motif) ligand 21A (serine); ALP; SLC; plt; CKb9;Tca4; 6Ckine; Scya21; 6CKBAC2; SCYA21a; Scya21b; AW987545; OTTMUSP00000006949;Exodus-2; C-C motif chemokine 21a;CCL21-Ser; CC chemokine 6Ckine-ser; beta chemokineexodus-2; beta-chemokine exodus-2; smallinducible cytokine A21a; small-inducible cytokine A21a; thymus-derivedchemotactic agent 4; TCA4
Gene ID : 18829
mRNA Refseq : NM_011124
Protein Refseq : NP_035254
UniProt ID : P844444
Chromosome Location : 4
Pathway : Chemokine receptorsbind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-likereceptors); Cytokine-cytokine receptor interaction; G alpha (i) signallingevents; GPCR downstream signaling; GPCR ligand binding; Peptideligand-binding receptors; Signal Transduction; Signaling by GPCR
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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