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CCL4L2

Official Full Name

chemokine (C-C motif) ligand 4-like 2
Overview

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
Synonyms

CCL4L2; chemokine (C-C motif) ligand 4-like 2; CC chemokine ligand 4L2; CC chemokine ligand 4L1d2; lymphocyte activation gene 1; macrophage inflammatory protein-1b2; chemokine (C-C motif) ligand 4-like 1, telomeric; CCL4L; SCYA4L; AT744.2;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CCL4L2-627H	Active Recombinant Human CCL4L2	E.coli	N/A		Inquiry
Human	CCL4L2-27831TH	Recombinant Human CCL4L2, His-tagged	E.coli	His	69 amino acids	Inquiry
Human	CCL4L2-1189H	Recombinant Human CCL4L2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein

CCL4L2 involved in several pathways and played different roles in them. We selected most pathways CCL4L2 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, NF-kappa B signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCL4L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cytokine-cytokine receptor interaction	RNF207B;BMP7B;KITLGB;XCR1;PRL2;FLT1;IFNA8;Il2;IFNGR2
Chemokine signaling pathway	MAPK1;GM10591;CRK;ITK;CXCL6;CCL11;LOC100033925;NCF1;GNG13
NF-kappa B signaling pathway	CD14;BCL2L1;TRAF5;TRAF1;IKBKB;PIAS4;BIRC2;ZAP70;XIAP
Toll-like receptor signaling pathway	CD14;PIK3R1;IFNA12;PIK3R3B;CCL3;IL6;RIPK1L;PIK3R5;IL12BA
Cytosolic DNA-sensing pathway	IL1B;IFNB1;RELA;TREX1;CASPA;IFNA8;Ifna15;CXCL10;POLR3H
Salmonella infection	CASP1;MAPK12;MAPK8;WAS;CXCL1;PFN4;ACTB1;DYNC1I1;RHOG

CCL4L2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by CCL4L2 itself. We selected most functions CCL4L2 had, and list some proteins which have the same functions with CCL4L2. You can find most of the proteins on our site.

Function	Related Protein

CCL4L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCL4L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCL4L2.

SLC30A2