ccna2
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  • Official Full Name
  • cyclin A2
  • Background
  • The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a;dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases.Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination;of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all;tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M;transitions.
  • Synonyms
  • CCNA2; cyclin A2; CCN1, CCNA; cyclin-A2; cyclin-A; CCN1; CCNA
Cat.#:CCNA2-0648HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCNA2 Protein, GST-Tagged
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Cat.#:CCNA2-31453THTag:
Source (Host):Species:Human
Product nameRecombinant Human CCNA2
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Cat.#:CCNA2-586HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human CCNA2 protein, GST-tagged
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Cat.#:CCNA2-6798HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Cyclin A2, His-tagged
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Cat.#:CCNA2-2982MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CCNA2 Protein
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Cat.#:CCNA2-696RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CCNA2 Protein, His-tagged
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Cat.#:CCNA2-6797CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CCNA2
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Cat.#:CCNA2-9416ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CCNA2
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Cat.#:CCNA2-256HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Cyclin A2, GST-tagged
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Cat.#:CCNA2-7718HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CCNA2 293 Cell Lysate
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Involved Pathway

CCNA2 involved in several pathways and played different roles in them. We selected most pathways CCNA2 participated on our site, such as Cell cycle, AMPK signaling pathway, Progesterone-mediated oocyte maturation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CCNA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell cycle
RBBP7; MAU2; NCAPG; CDT1; MPEG1.1; TGFB2; ORC5; KIF18A; RAD21B; MCM9
AMPK signaling pathway
INS2; PPP2R2A; PRKAB2; PFKP; PPP2R3C; PIK3CB; PIK3R1; PPP2R3A; PDPK1; MLYCD
Progesterone-mediated oocyte maturation
AKT2; RPS6KA3B; MAPK12; CCNA1; MAPK8; MAPK12A; CPEB1A; MAPK14B; PIK3CB; CPEB1
Hepatitis B
PIK3CB; IFNA8; TNF; BCL2; TRP53; NFATC1; TLR3; CASP10; Ifna11; TGFB2
Epstein-Barr virus infection
PSMC1; MAP2K4; PSMD7; SKP2; CSNK2B; NFKBIA; NUP214; ENTPD8; HLA-DRB5; PSMC6
Viral carcinogenesis
CCNA1; IRF3; TBP; SRC; HIST1H2BB; RHOA; GTF2B; CREB3L3; GTF2H2C_2; IRF7

Protein Function

CCNA2 has several biochemical functions, for example, protein binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CCNA2 itself. We selected most functions CCNA2 had, and list some proteins which have the same functions with CCNA2. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein FAM212A; PTCRA; IL17RE; AHCY; SPTLC1; MAGOHB; KIF2C; CTAG1B; TSR2; UNC119B
Function protein kinase binding
Related Protein PAX6; DLG1L; SKI; EMP2; NEFH; PDPK1; TTN; ARHGEF7; SKAP1; PARP1

Interacting Protein

CCNA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CCNA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CCNA2.
CDK2