ccr10

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ccr10

Official Full Name chemokine (C-C motif) receptor 10
Background Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
Synonyms CCR10; chemokine (C-C motif) receptor 10; GPR2; C-C chemokine receptor type 10; CCR-10; CC-CKR-10; C-C CKR-10; CC chemokine receptor 10; G protein-coupled receptor 2; G-protein coupled receptor 2;
    • Species :
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E. coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCR10-0687H Recombinant Human CCR10 Protein Wheat Germ N/A
    Human CCR10-0688H Recombinant Human CCR10 Protein, GST-Tagged Wheat Germ GST
    Human CCR10-17H Recombinant Human CCR10 Protein, His-tagged E. coli His
    Human CCR10-7697HCL Recombinant Human CCR10 293 Cell Lysate HEK293 N/A
    Mouse CCR10-3012M Recombinant Mouse CCR10 Protein Mammalian Cell His
    Zebrafish CCR10-782Z Recombinant Zebrafish CCR10 Mammalian Cell His
    Kit-0926 ER Beta Competitor Assay Kit, Green N/A
    Kit-1148 CCR10 Activated GPCR Internalization Assay Kit N/A
    Kit-1149 CCR10 U2OS β-Arrestin GPCR Assay Kit N/A

    ccr10 involved in several pathways and played different roles in them. We selected most pathways ccr10 participated on our site, such as Cytokine-cytokine receptor interaction, Chemokine signaling pathway, Intestinal i, which may be useful for your reference. Also, other proteins which involved in the same pathway with ccr10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction ACVR2AA; IFNA3; IL2RGB; LIFRA; CXCL11; GH2; CXCL14; TNFRSF12A; TNFSF4; IL2RB
    Chemokine signaling pathway CXCL5; PAK1; SHC1; DOCK2; CXCR2; CCL19; CCL21; GRK6; STAT5B; CXCL2
    Intestinal i HLA-DQA2; BLB2; MHC2DAB; H2-AA; HLA-DRB3; TNFRSF13B; CD40; CXCR4A; IL4; MHC2DEB
    ne network for IgA production CXCR4A; BMA1; IL15; HLA-DPA1; CD40; TGFB1A; CXCR4; HLA-DMB; CCR10; HLA-DOB

    ccr10 has several biochemical functions, for example, C-C chemokine receptor activity, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ccr10 itself. We selected most functions ccr10 had, and list some proteins which have the same functions with ccr10. You can find most of the proteins on our site.

    Function Related Protein
    C-C chemokine receptor activity GPR75; CCR10; CCR6A; CCR1L1; CCBP2; CCR9; CCR3; CCR1; CCR6; CCR5
    G-protein coupled receptor activity V2RX1; FZD7B; VMN1R46; PTGER2B; OR6Q1; GPR97; GPR162; OLFR493; OR5B2; OR4F29

    ccr10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ccr10 here. Most of them are supplied by our site. Hope this information will be useful for your research of ccr10.

    FYN; NCK1; GRB2; PRRC2A

    Thomas, MA; Buelow, BJ; et al. Structure-Function Analysis of CCL28 in the Development of Post-viral Asthma. JOURNAL OF BIOLOGICAL CHEMISTRY 290:4528-4536(2015).
    McKinnon, LR; Nyanga, B; et al. Early HIV-1 Infection Is Associated With Reduced Frequencies of Cervical Th17 Cells. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 68:6-12(2015).

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