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Official Full Name chemokine (C-C motif) receptor 8
Background CCR8 (C-C chemokine receptor 8, CKR-L1, cy6) is a member of the beta-chemokine receptor family that is preferentially expressed in the thymus. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites
Synonyms CCR8; chemokine (C-C motif) receptor 8; CMKBR8, CMKBRL2; C-C chemokine receptor type 8; CDw198; CKR L1; CY6; GPR CY6; TER1; CC chemokine receptor 8; chemokine receptor-like 1; chemokine (C-C) receptor 8; CC chemokine receptor CHEMR1; CC-chemokine receptor
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CCR8-0697H Recombinant Human CCR8 Protein Wheat Germ N/A
    Human CCR8-0698H Recombinant Human CCR8 Protein, GST-Tagged Wheat Germ GST
    Mouse CCR8-3018M Recombinant Mouse CCR8 Protein Mammalian Cell His
    Cynomolgus Monkey CCR8-380C Recombinant Cynomolgus CCR8 Protein, His-tagged Mammalian Cell His
    Chicken CCR8-2675C Recombinant Chicken CCR8 Mammalian Cell His
    Kit-0878 ADK Phosphorylation Assay Kit N/A
    Kit-1162 CCR8 CHO-K1 β-Arrestin GPCR Assay Kit N/A

    ccr8 involved in several pathways and played different roles in them. We selected most pathways ccr8 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with ccr8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chemokine receptors bind chemokines CCR3; CXCR6; CCL27; CCR8; AMCF-II; CXCL11.8; CCR1; ACKR4; CCR9; CXCR7B
    Chemokine signaling pathway GNAI3; NFKB1; XCL2; SHC4; MAPK3; GM13306; CCR10; CCL13; PIK3CA; STAT2
    Class A/1 (Rhodopsin-like receptors) OPN1LW; UTS2D; KISS1; APLN; EDNRB; ADRA2C; RLN3A; OPN1SW1; GPR65; QRFP
    Cytokine-cytokine receptor interaction CD40LG; IL11; IFNK; INHBC; IL13RA1; IL1A; CNTFR; IL22RA2; ACVR1B; GH2
    G alpha (i) signalling events DRD3; OXGR1A.3; ADRA2A; FPR-RS6; GPR55; GAL; OPN1LW1; SSTR1; S1PR5B; POMCB
    GPCR downstream signaling OPN4.1; OR10A5; VIP; SCT; ARHGEF1A; GRP; NMBB; CASR; ADCYAP1R1; ARHGEF17
    GPCR ligand binding GPR17; EDN1; GHRH; TRH; PROKR1; GAL; GPR55; OPN1SW1; PROK2; GPR4
    GPCRs, Class A Rhodopsin-like NMUR1; GPR1; CNR1; FPR-RS3; CCBP2; OR10A5; CYSLTR1; OPN1LW; GPR18; CCR3

    ccr8 has several biochemical functions, for example, C-C chemokine receptor activity, chemokine receptor activity, coreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ccr8 itself. We selected most functions ccr8 had, and list some proteins which have the same functions with ccr8. You can find most of the proteins on our site.

    Function Related Protein
    C-C chemokine receptor activity CCR3; GPR75; CCR5; CCR10; CCR1; CCR8; CCR7; CCBP2; CCR1L1; CCR6
    chemokine receptor activity CCRL2; CMKLR1; CCR6A; CXCR3.1; ACKR4; CXCR4A; CX3CR1; CXCR1; CCR9; CCR3
    coreceptor activity RAMP1; CXCR7; PVRL1; TGFBR3; LY96; CD4; ACKR3B; CXCR4; HFE2; CD28

    ccr8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ccr8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ccr8.

    Santos-Costa, Q; Lopes, MM; et al. HIV-2 interaction with cell coreceptors: amino acids within the V1/V2 region of viral envelope are determinant for CCR8, CCR5 and CXCR4 usage. RETROVIROLOGY 11:-(2014).
    Zhou, JH; Kang, N; et al. Anti-gamma delta TCR antibody-expanded gamma delta T cells: a better choice for the adoptive immunotherapy of lymphoid malignancies. CELLULAR & MOLECULAR IMMUNOLOGY 9:34-44(2012).

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