Cd180

  • Official Full Name

    CD180 antigen

  • Overview

    CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail.;The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex,;RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in;concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of;Gram-negative bacteria.
  • Synonyms

    CD180; CD180 antigen; ly-78; lymphocyte antigen 78; radioprotective 105 kDa protein; Ly78; RP105; F630107B15;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Rhesus monkey
  • E.coli
  • HEK293
  • Human Cell
  • Insect Cell
  • Mammalian cells
  • C
  • His
  • Fc
  • hFc
  • hIgG1
  • hIgG4
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD180-3900H Recombinant Human CD180 protein, His-tagged HEK293 His Met1-Gly626
Human CD180-10915H Recombinant Human CD180, His-tagged E.coli His C-term-348a.a.
Human CD180-2099HCL Recombinant Human CD180 cell lysate Human Cell N/A
Human CD180-3064H Recombinant Human CD180 protein, His-tagged E.coli His 164-389 aa
Human CD180-4475H Recombinant Human CD180 Protein (Met1-Gly626), C-His tagged Mammalian cells C-His Met1-Gly626
Human CD180-655H Recombinant Human CD180 Protein, His-tagged E.coli N-His Asp288-Asp620
Human CD180-096H Recombinant Human CD180 Protein, C-His-tagged E.coli C-His
Human CD180-1396H Recombinant Human CD180 Protein (Thr430-Gly626), N-His tagged E.coli N-His Thr430-Gly626
Mouse Cd180-3305M Recombinant Mouse Cd180 protein, His-tagged HEK293 His Met1-Ser626
Mouse Cd180-3260M Recombinant Mouse Cd180 protein, hFc-tagged HEK293 hFc Met1-Ser626
Mouse Cd180-3261M Recombinant Mouse Cd180 protein, Fc-tagged Insect Cell Fc Thr21 - Ser626
Mouse CD180-2224MCL Recombinant Mouse CD180 cell lysate Human Cell N/A
Mouse CD180-2225MCL Recombinant Mouse CD180 cell lysate Human Cell N/A
Rhesus monkey CD180-1600R Recombinant Rhesus Monkey CD180 Protein, hIgG4-tagged HEK293 hIgG4
Rhesus monkey CD180-1598R Recombinant Rhesus Monkey CD180 Protein HEK293 N/A
Rhesus monkey CD180-1599R Recombinant Rhesus Monkey CD180 Protein, hIgG1-tagged HEK293 hIgG1
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

Cd180 involved in several pathways and played different roles in them. We selected most pathways Cd180 participated on our site, such as Immune System, Innate Immune System, Toll Like Receptor 4 (TLR4) Cascade, which may be useful for your reference. Also, other proteins which involved in the same pathway with Cd180 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Immune SystemSEC23A;IFI6;POLR3F;DUSP3B;TREX1;HLA-DQB2;LAIR2;PJA1;TAX1BP1
Innate Immune SystemS100A12;ABI1;MYO9B;RIPK3;CHST13;DEFB104A;NLRP4B;DEFA5;CLEC4D
Toll Like Receptor 4 (TLR4) CascadeCD180;LY86;SIGIRR
Toll-Like Receptors CascadesCD180;CTS7;TNRC5;UNC93B1;CNPY3;LY86

Cd180 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by Cd180 itself. We selected most functions Cd180 had, and list some proteins which have the same functions with Cd180. You can find most of the proteins on our site.

Function Related Protein

Cd180 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Cd180 here. Most of them are supplied by our site. Hope this information will be useful for your research of Cd180.

Research Area

Related articles

Huang, PY; Best, OG; et al. Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia. LEUKEMIA & LYMPHOMA 55:2085-2092(2014).
Karper, JC; de Jager, SCA; et al. An Unexpected Intriguing Effect of Toll-Like Receptor Regulator RP105 (CD180) on Atherosclerosis Formation With Alterations on B-Cell Activation. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 33:2810-2817(2013).
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