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Recombinant Human CD180 Protein, C-His-tagged

Cat.No. : CD180-096H
Product Overview : Recombinant Human CD180 Protein with C-His tag was expressed in E. coli.
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Description : CD180/RP105 is a type-I transmembrane glycoprotein that is restricted to expression in mature B-cells. Research studies have shown that CD180 engages signaling cascades in mature B-cells that drive cell proliferation. Indeed, CD180 functions with TLR4 as an LPS receptor on B-cells and, upon binding LPS, transmits proliferation and survival signals that require the Vav family of guanine nucleotide exchange factors.
Source : E. coli
Species : Human
Tag : His
Molecular Mass : ~66 kDa
AA Sequence : WDQMCIEKEANKTYNCENLGLSEIP DTLPNTTEFLEFSFNFLPTIHNRTF SRLMNLTFLDLTRCQINWIHEDTFQ SHHQLSTLVLTGNPLIFMAETSLNG PKSLKHLFLIQTGISNLEFIPVHNL ENLESLYLGSNHISSIKFPKDFPAR NLKVLDFQNNAIHYISREDMRSLEQ AINLSLNFNGNNVKGIELGAFDSTI FQSLNFGGTPNLSVIFNGLQNSTTQ SLWLGTFEDIDDEDISSAMLKGLCE MSVESLNLQEHRFSDISSTTFQCFT QLQELDLTATHLKGLPSGMKGLNLL KKLVLSVNHFDQLCQISAANFPSLT HLYIRGNVKKLHLGVGCLEKLGNLQ TLDLSHNDIEASDCCSLQLKNLSHL QTLNLSHNEPLGLQSQAFKECPQLE LLDLAFTRLHINAPQSPFQNLHFLQ VLNLTYCFLDTSNQHLLAGLPVLRH LNLKGNHFQDGTITKTNLLQTVGSL EVLILSSCGLLSIDQQAFHSLGKMS HVDLSHNSLTCDSIDSLSHLKGIYL NLAANSINIISPRLLPILSQQSTIN LSHNPLDCTCSNIHFLTWYKENLHK LEGSEETTCANPPSLRGVKLSDVKL SCG
Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).
Notes : For research use only, not for use in diagnostic procedure.
Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles.
Concentration : ≥0.5 mg/mL
Storage Buffer : PBS, 4M Urea, pH7.4
Gene Name : CD180 CD180 molecule [ Homo sapiens (human) ]
Official Symbol : CD180
Synonyms : CD180; CD180 molecule; CD180 antigen , LY64, lymphocyte antigen 64 (mouse) homolog, radioprotective, 105kD; CD180 antigen; Ly78; RP105; lymphocyte antigen 64; radioprotective 105 kDa protein; lymphocyte antigen-64, radioprotective, 105kDa; LY64; MGC126233; MGC126234;
Gene ID : 4064
mRNA Refseq : NM_005582
Protein Refseq : NP_005573
MIM : 602226
UniProt ID : Q99467

Not For Human Consumption!

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