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Official Full Name cell division cycle 16 homolog (S. cerevisiae)
Background This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein and two other APC complex proteins, CDC23 and CDC27, contain a tetratricopeptide repeat (TPR), a protein domain that may be involved in protein-protein interaction. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms CDC16; cell division cycle 16 homolog (S. cerevisiae); CDC16 (cell division cycle 16, S. cerevisiae, homolog) , CDC16 cell division cycle 16 homolog (S. cerevisiae); cell division cycle protein 16 homolog; ANAPC6; anaphase promoting complex; subunit 6; APC6; CUT9; Anaphase promoting complex subunit 6; Anaphase-promoting complex subunit 6; Apc 6; CDC 16; CDC16 (cell division cycle 16 S. cerevisiae homolog); CDC16 homolog; CDC16 protein; CDC16_HUMAN; CDC16Hs; Cell division cycle 16 homolog; Cyclosome subunit 6; anaphase-promoting complex, subunit 6
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDC16-0902H Recombinant Human CDC16 Protein, GST-Tagged Wheat Germ GST
    Human CDC16-1270H Recombinant Human CDC16 protein, His & T7-tagged E.coli His/T7
    Human CDC16-3535H Recombinant Human CDC16 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CDC16-5809H Recombinant Human CDC16 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CDC16-7669HCL Recombinant Human CDC16 293 Cell Lysate HEK293 N/A
    Human CDC16-7670HCL Recombinant Human CDC16 293 Cell Lysate HEK293 N/A
    Mouse Cdc16-2072M Recombinant Mouse Cdc16 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rhesus Macaque CDC16-757R Recombinant Rhesus monkey CDC16 Protein, His-tagged Mammalian Cell His
    Chicken CDC16-1412C Recombinant Chicken CDC16 Mammalian Cell His
    Zebrafish CDC16-3514Z Recombinant Zebrafish CDC16 Mammalian Cell His

    cdc16 involved in several pathways and played different roles in them. We selected most pathways cdc16 participated on our site, such as Cell cycle, Oocyte meiosis, Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdc16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cell cycle TP53BP1; MCM3; E2F5; RUVBL2; YWHAQ; SETA; GINS2; MCM9; WAPAL; CLSPN
    Oocyte meiosis IGF1RA; PRKACBB; PPP1CA; INS1; SMC1B; RPS6KA3B; YWHAQB; PPP3R2; CDC20; FBXO43
    Ubiquitin mediated proteolysis CDC34; UBE2W; CUL4A; UBE3C; UBE2R2; UBA7; UBR5; ANAPC11; PIAS4A; BIRC3
    Progesterone-mediated oocyte maturation HSP90AA1.1; ADCY1B; PIK3R3A; MAPK14A; PRKACB; CCNA2; INS2; CDC25B; PRKACBB; ANAPC5
    HTLV-I infection PPP3CA; CREM; WNT9B; VAC14; HLA-DPA1; NFATC2; Adcy4; VCAM1; TGFB1; PIK3CA

    cdc16 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdc16 itself. We selected most functions cdc16 had, and list some proteins which have the same functions with cdc16. You can find most of the proteins on our site.

    Function Related Protein
    protein binding RIPK2; JRK; DHX15; LRP1; ACPL2; AARSD1; GFOD1; FAS; ACAP1; ALDH1A2

    cdc16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdc16 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdc16.

    CDC26; CDC27; CDC20; ANAPC1

    Imai, A; Yoshie, S; et al. EPI64 Protein Functions as a Physiological GTPase-activating Protein for Rab27 Protein and Regulates Amylase Release in Rat Parotid Acinar Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 286:33854-33862(2011).
    Luo, Y; Sarabi, SA; et al. Expression pattern of NuIP gene in adult mouse brain. BRAIN RESEARCH 1302:42-53(2009).

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