cdc37

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cdc37

Official Full Name cell division cycle 37 homolog
Background CDC37 is an important component of the HSP90 chaperone complex. It was initially identified for its involvement in cell-cycle progression and was later found to have a much broader role as a chaperone for a wide variety of kinases and other proteins. CDC3
Synonyms CDC37; cell division cycle 37 homolog (S. cerevisiae); CDC37 (cell division cycle 37, S. cerevisiae, homolog) , CDC37 cell division cycle 37 homolog (S. cerevisiae); hsp90 co-chaperone Cdc37; CDC37 (cell division cycle 37; S. cerevisiae; homolog)
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDC37-0930H Recombinant Human CDC37 Protein, GST-Tagged Wheat Germ GST
    Human CDC37-11006H Recombinant Human CDC37, GST-tagged E.coli GST
    Human CDC37-124H Recombinant Human CDC37 protein, T7/His-tagged E.coli T7/His
    Human CDC37-26222TH Recombinant Human CDC37, His-tagged E.coli His
    Human CDC37-3072H Recombinant Human CDC37, GST tagged Insect Cell GST
    Human CDC37-3124H Recombinant Human CDC37 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human CDC37-331H Recombinant Human Cell Division Cycle 37 Homolog (S. cerevisiae) E.coli N/A
    Human CDC37-648HCL Recombinant Human CDC37 cell lysate Insect Cell N/A
    Human CDC37-798H Recombinant Human, CDC37 His-tagged E.coli His
    Mouse CDC37-001MCL Recombinant Mouse CDC37 cell lysate Insect Cell N/A
    Mouse CDC37-403M Recombinant Mouse Cdc37, Gly & Pro tagged Insect Cell His
    Mouse CDC37-417M Recombinant Mouse Cdc37, His-GST tagged Insect Cell Fc
    Mouse Cdc37-855M Recombinant Mouse Cdc37 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Rat CDC37-1275R Recombinant Rat CDC37 Protein Mammalian Cell His
    Chicken CDC37-6260C Recombinant Chicken CDC37 Mammalian Cell His
    Zebrafish CDC37-11269Z Recombinant Zebrafish CDC37 Mammalian Cell His

    cdc37 involved in several pathways and played different roles in them. We selected most pathways cdc37 participated on our site, such as AhR pathway, Constitutive Signaling by EGFRvIII, Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdc37 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    AhR pathway FLG; PTGES3; CYP1A2; AIP; CDKN1A; CDKN1B; CDC37; NQO1; EGFR; CYP1B1
    Constitutive Signaling by EGFRvIII CDC37
    Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants CDC37
    Disease MMADHC; MYO18A; TAF1L; OPN1LW; FDX1L; OPN1MW; TLR6; CTBP2; PPIA; MMAA
    Diseases of signal transduction LRRFIP1; RLBP1; TNKS2; TTR; KREMEN2; CCNC; RBP4; CTBP2; FKBP1A; STRA6
    LKB1 signaling events STK11IP; CTSD; MARK2; MARK4; MAP2; CDC37; SIK3
    PI3K-Akt signaling pathway COMP; CSF3R; CSF1R; SGK2; LAMC3; PRP2; CSH; EFNA4; LOC608458; CSH1
    Signal Transduction RGS4; LINGO1B; CHN2; RGS9BP; ABCA4A; KDM4C; CALML4; GPR177; HCRT; SOX4A

    cdc37 has several biochemical functions, for example, Hsp90 protein binding, chaperone binding, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cdc37 itself. We selected most functions cdc37 had, and list some proteins which have the same functions with cdc37. You can find most of the proteins on our site.

    Function Related Protein
    Hsp90 protein binding UNC45B; CDC37; ARNTL; ERBB2; PACRG; FKBP6; EIF2AK3; STUB1; RPS3; UNC45A
    chaperone binding DNAJB6; HYOU1; ATP1A1; HSPE1; CLU; DNAJA3A; BAG5; TRP53; VWF; TBCA
    heat shock protein binding LIMK1; PPP5C; FAF1; DNAJA2L; PACRG; CDC37L1; DLST; EEF1D; NFKB1; FKBP5
    kinase binding TOLLIP; PRDX3; DLG3; RB1; WWC2; DUSP12; PARK7; EMP2; WWC1; PFKM
    mitogen-activated protein kinase kinase kinase binding MAP2K1; MAPK8IP3; PPEF2; TRAF6; CDC37; CDC42; STK38; MAPK9; DUSP19; MAP4K2
    protein C-terminus binding MYO1C; SDCBP; PXK; ITPR1; PRKAA1; C11orf60; PIAS3; VAMP2; SIRT1; CDC37
    protein binding ZYX; ATRX; ACTN3; KIRREL; BATF3; ATF7IP; ZC3HC1; VAC14; MAP2K4; NAA10
    protein kinase B binding PINK1; CDC37; CCDC88A; APPL1; RARA; ANKRD2; PDE3B; BAD; BCL10; TRAF6
    protein kinase regulator activity CDK5RAP1; APC; FAF1; KIDINS220B; CSNK2B; RAC2; CDC37; ANKRD54; KIDINS220
    unfolded protein binding CHAF1A; SSUH2.2; SERPINH1; LRPAP1; DNAJB5; APCS; DNAJB1; NDUFAF1; TBCA; CCT7

    cdc37 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdc37 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdc37.

    HSP90AA1; LRRK2

    Cao, FF; Xu, LM; et al. IP-FCM Platform Detects the Existence and Regulator-Caused Dissociation of Components in Naturally Assembled HSP90 Complex. CYTOMETRY PART A 85:359-367(2014).
    Du, C; Wingard, JR; et al. Serum IgG Responses against Aspergillus Proteins before Hematopoietic Stem Cell Transplantation or Chemotherapy Identify Patients Who Develop Invasive Aspergillosis. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION 18:1927-1934(2012).

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