Recombinant Full Length Human CDC37 Protein, C-Flag-tagged

• Cat.No.: CDC37-2013HFL
• Product Overview: Recombinant Full Length Human CDC37 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 44.3 kDa
• AA Sequence: MVDYSVWDHIEVSDDEDETHPNIDT ASLFRWRHQARVERMEQFQKEKEEL DRGCRECKRKVAECQRKLKE LEVAEGGKAELERLQAEAQQLRKEE RSWEQKLEEMRKKEKSMPWNVDTLS KDGFSKSMVNTKPEKTEEDS EEVREQKHKTFVEKYEKQIKHFGML RRWDDSQKYLSDNVHLVCEETANYL VIWCIDLEVEEKCALMEQVA HQTIVMQFILELAKSLKVDPRACFR QFFTKIKTADRQYMEGFNDELEAFK ERVRGRAKLRIEKAMKEYEE EERKKRLGPGGLDPVEVYESLPEEL QKCFDVKDVQMLQDAISKMDPTDAK YHMQRCIDSGLWVPNSKASE AKEGEEAGPGDPLLEAVPKTGDEKD VSV TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Gene Information

• Gene Name: CDC37 cell division cycle 37, HSP90 cochaperone [ Homo sapiens (human) ]
• Official Symbol: CDC37
• Synonyms: P50CDC37
• Gene ID: 11140
• mRNA Refseq: NM_007065.4
• Protein Refseq: NP_008996.1
• MIM: 605065
• UniProt ID: Q16543