Recombinant Human CDH10, His-tagged
| Cat.No. : | CDH10-26741TH |
| Product Overview : | Recombinant fragment, corresponding to amino acids 228-514 of Human cadherin 10 with N terminal His tag; MWt 33kDa. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His |
| Protein Length : | 228-514 a.a. |
| Description : | This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the proteins homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance. |
| Conjugation : | HIS |
| Form : | Lyophilised:Reconstitute with 147 μl aqua dest. |
| Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | ENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPP RFPQNTIHLRVLESSPVGTAIGSVKATDADTGKNAEVE YRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRL YTLKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEP PVFSRSSYLFEVHEDIEVGTIIGTVMARDPDSISSPIRFS LDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTV IAAEINNPKETTRVAVFVRILDVNDNAPQFAVFYDTFV CENARPGQLIQTISAVD |
| Gene Name | CDH10 cadherin 10, type 2 (T2-cadherin) [ Homo sapiens ] |
| Official Symbol | CDH10 |
| Synonyms | CDH10; cadherin 10, type 2 (T2-cadherin); cadherin-10; |
| Gene ID | 1008 |
| mRNA Refseq | NM_006727 |
| Protein Refseq | NP_006718 |
| MIM | 604555 |
| Uniprot ID | Q9Y6N8 |
| Chromosome Location | 5p14.2 |
| Pathway | Adherens junctions interactions, organism-specific biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; |
| Function | calcium ion binding; |
Not For Human Consumption!
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