Recombinant Human CDH18 Protein, His-tagged

• Cat.No.: CDH18-718H
• Product Overview: Recombinant Human CDH18 Protein (Gly54-Phe268) with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Gly54-Phe268
• Description: This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.4 kDa; Accurate Molecular Mass: 32 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: CDH18 cadherin 18, type 2 [ Homo sapiens (human) ]
• Official Symbol: CDH18
• Synonyms: CDH18; cadherin 18, type 2; cadherin-18; CDH14; EY CADHERIN; cadherin-14; ey-cadherin; cadherin-like 24; CDH24; CDH14L
• Gene ID: 1016
• mRNA Refseq: NM_001167667
• Protein Refseq: NP_001161139
• MIM: 603019
• UniProt ID: Q13634