Recombinant Human CDH23 Protein

• Cat.No.: CDH23-0986H
• Product Overview: Human CDH23 full-length ORF (ADZ15527.1) recombinant protein without tag.

Specification

• Description: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 116.8 kDa
• AA Sequence: MGRHVATSCHVAWLLVLISGCWGQV NRLPFFTNHFFDTYLLISEDTPVGS SVTQLLAQDMDNDPLVFGVSGEEAS RFFAVEPDTGVVWLRQPLDRETKSE FTVEFSVSDHQGVITRKVNIQVGDV NDNAPTFHNQPYSVRIPENTPVGTP IFIVNATDPDLGAGGSVLYSFQPPS QFFAIDSARGIVTVIRELDYETTQA YQLTVNATDQDKTRPLSTLANLAII ITDVQDMDPIFINLPYSTNIYEHSP PGTTVRIITAIDQDKGRPRGIGYTI VSGNTNSIFALDYISGVLTLNGLLD RENPLYSHGFILTVKGTELNDDRTP SDATVTTTFNILVIDINDNAPEFNS SEYSVAITELAQVGFALPLFIQVVD KDENLGLNSMFEVYLVGNNSHHFII SPTSVQGKADIRIRVAIPLDYETVD RYDFDLFANESVPDHVGYAKVKITL INENDNRPIFSQPLYNISLYENVTV GTSVLTVLATDNDAGTFGEVSYFFS DDPDRFSLDKDTGLIMLIARLDYEL IQRFTLTIIARDGGGEETTGRVRIN VLDVNDNVPTFQKDAYVGALRENEP SVTQLVRLRATDEDSPPNNQITYSI VSASAFGSYFDISLYEGYGVISVSR PLDYEQISNGLIYLTVMAMDAGNPP LNSTVPVTIEVFDENDNPPTFSKPA YFVSVVENIMAGATVLFLNATDLDR SREYGQESIIYSLEGSTQFRINARS GEITTTSLLDRETKSEYILIVRAVD GGVGHNQKTGIATVNITLLDINDNH PTWKDAPYYINLVEMTPPDSDVTTV VAVDPDLGENGTLVYSIQPPNKFYS LNSTTGKIRTTHAMLDRENPDPHEA ELMRKIVVSVTDCGRPPLKATSSAT VFVNLLDLNDNDPTFQNLPFVAEVL EGIPAGVSIYQVVAIDLDEGLNGLV SYRMPVGMPRMDFLINSSSGVVVTT TELDRERIAEYQLRVVASDAGTPTK SSTSTLTIHVLDVNDETPTFFPAVY NVSVSEDVPREFRVVWLNCTDNDVG LNAELSYFITGAAPASAHLCRPPGA LPPPLPDGQPD
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: CDH23 cadherin-related 23 [ Homo sapiens ]
• Official Symbol: CDH23
• Synonyms: CDH23; cadherin-related 23; cadherin related 23, cadherin like 23, DFNB12, USH1D; cadherin-23; cadherin related family member 23; CDHR23; otocadherin; cadherin-like 23; cadherin-related family member 23; USH1D; FLJ00233; FLJ36499; KIAA1774; KIAA1812; MGC102761; DKFZp434P2350
• Gene ID: 64072
• mRNA Refseq: NM_001171930
• Protein Refseq: NP_001165401
• MIM: 605516
• UniProt ID: Q9H251