Recombinant Human CDH8 Protein, GST-Tagged

• Cat.No.: CDH8-0995H
• Product Overview: Human CDH8 full-length ORF (NP_001787.2, 1 a.a. - 799 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 114.7 kDa
• AA Sequence: MPERLAEMLLDLWTPLIILWITLPP CIYMAPMNQSQVLMSGSPLELNSLG EEQRILNRSKRGWVWNQMFVLEEFS GPEPILVGRLHTDLDPGSKKIKYIL SGDGAGTIFQINDVTGDIHAIKRLD REEKAEYTLTAQAVDWETSKPLEPP SEFIIKVQDINDNAPEFLNGPYHAT VPEMSILGTSVTNVTATDADDPVYG NSAKLVYSILEGQPYFSIEPETAII KTALPNMDREAKEEYLVVIQAKDMG GHSGGLSGTTTLTVTLTDVNDNPPK FAQSLYHFSVPEDVVLGTAIGRVKA NDQDIGENAQSSYDIIDGDGTALFE ITSDAQAQDGIIRLRKPLDFETKKS YTLKVEAANVHIDPRFSGRGPFKDT ATVKIVVEDADEPPVFSSPTYLLEV HENAALNSVIGQVTARDPDITSSPI RFSIDRHTDLERQFNINADDGKITL ATPLDRELSVWHNITIIATEIRNHS QISRVPVAIKVLDVNDNAPEFASEY EAFLCENGKPGQVIQTVSAMDKDDP KNGHYFLYSLLPEMVNNPNFTIKKN EDNSLSILAKHNGFNRQKQEVYLLP IIISDSGNPPLSSTSTLTIRVCGCS NDGVVQSCNVEAYVLPIGLSMGALI AILACIILLLVIVVLFVTLRRHKNE PLIIKDDEDVRENIIRYDDEGGGEE DTEAFDIATLQNPDGINGFLPRKDI KPDLQFMPRQGLAPVPNGVDVDEFI NVRLHEADNDPTAPPYDSIQIYGYE GRGSVAGSLSSLESTTSDSDQNFDY LSDWGPRFKRLGELYSVGESDKET
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CDH8 cadherin 8, type 2 [ Homo sapiens ]
• Official Symbol: CDH8
• Synonyms: CDH8; cadherin 8, type 2; cadherin-8; Nbla04261
• Gene ID: 1006
• mRNA Refseq: NM_001796
• Protein Refseq: NP_001787
• MIM: 603008
• UniProt ID: P55286