|Official Full Name||cyclin-dependent kinase 6|
|Background||The cyclin-dependent kinases form complexes with their cyclin partners and with CDK inhibitors. CDK6 and CDK4 associate with the D-type cyclins and target the retinoblastoma protein, allowing passage through the G1/S phase restriction point (1). CDK6/cycl|
|Synonyms||CDK6; cyclin-dependent kinase 6; PLSTIRE; cell division protein kinase 6; serine/threonine-protein kinase PLSTIRE; MGC59692|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cdk6 involved in several pathways and played different roles in them. We selected most pathways cdk6 participated on our site, such as B Cell Receptor Signaling Pathway, C-MYB transcription factor network, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdk6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|B Cell Receptor Signaling Pathway||PTPN6; BANK1; BCL2L11; PRKCB; RAF1; CRK; IKBKB; AKT2; BLK; PPP3CA|
|C-MYB transcription factor network||SLC25A3; MYOD1; SMARCA2; PPID; PTCRA; CBX4; SKI; MYC; CREBBP; GATA1|
|Cell Cycle||PCNA; RBBP8; ORC6; TUBB4B; NUMA1; RAD9; PDS5B; CDC14A; GSK3B; GADD45B|
|Cell Cycle, Mitotic||DCTN2; OFD1; NDE1; TUBB4B; NDEL1; CEP152; GOLGA2; DCTN1; GMNN; GINS3|
|Cellular Senescence||TERF1; PHC2; PHC3; LMNB1; HIST1H1C; KAT5; RNF2; CDKN2D; CDK4; BMI1A|
|Cellular responses to stress||EP400; SUZ12; HIST2H3C; GABARAPL2; RBBP7; EGLN2; HIST1H1E; CBX6A; H3F3D; CDKN2C|
|Chronic myeloid leukemia||CBLB; MAP2K2; RAF1; TGFBR2; PIK3CD; PIK3R1; MAP2K1; SHC1; GAB2; PIK3R5|
cdk6 has several biochemical functions, for example, ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cdk6 itself. We selected most functions cdk6 had, and list some proteins which have the same functions with cdk6. You can find most of the proteins on our site.
|ATP binding||ADCK2; ABCG2D; CLP1; FANCM; P2RY1; PMS1; CKMT1; DDX25; CDC42BPB; CHD8|
|cyclin binding||MDFIC; PFTK1; CDK12; CDK2; CDK4; HDAC3; CDK5RAP3; CDKN1A; PTCH1; USP2|
|cyclin-dependent protein serine/threonine kinase activity||NAT1; CCNK; CDK1; CDK9; CDK15; CDK17; CDKL5; CDK2; CDK14; CDK19|
|protein binding||STOM; HINT2; FGFRL1B; TAL1; COPG; ATL2; LCP2; RPL39L; ZNHIT6; MST1R|
cdk6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdk6 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdk6.