cdk6

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cdk6

Official Full Name cyclin-dependent kinase 6
Background The cyclin-dependent kinases form complexes with their cyclin partners and with CDK inhibitors. CDK6 and CDK4 associate with the D-type cyclins and target the retinoblastoma protein, allowing passage through the G1/S phase restriction point (1). CDK6/cycl
Synonyms CDK6; cyclin-dependent kinase 6; PLSTIRE; cell division protein kinase 6; serine/threonine-protein kinase PLSTIRE; MGC59692
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDK6-1883H Recombinant Human CDK6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human CDK6-3246H Recombinant Human CDK6 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Cdk6-867M Recombinant Mouse Cdk6 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CDK6/CCND1-277H Recombinant Human CDK6/CCND1, His-tagged, GST-tagged, Active Sf9 Insect Cell GST
    Human CDK6/CCND3-278H Recombinant Human CDK6/CCND3, His-tagged, Active Sf9 Insect Cell His
    Human CDK6-1002H Recombinant Human Cyclin-Dependent Kinase 6, His-tagged Sf9 Insect Cell His
    Human CDK6-1028H Recombinant Human CDK6 Protein, GST-Tagged Wheat Germ GST
    Human CDK6-1032H Recombinant Human CDK6 Protein, GST-Tagged Insect Cell GST
    Human CDK6-1537H Recombinant Human CDK6, Unactive, His-tagged Sf9 Insect Cell His
    Human CDK6-27908TH Recombinant Human CDK6, His-tagged His
    Human CDK6-7622HCL Recombinant Human CDK6 293 Cell Lysate HEK293 N/A
    Rhesus Macaque CDK6-788R Recombinant Rhesus monkey CDK6 Protein, His-tagged Mammalian Cell His
    Chicken CDK6-1791C Recombinant Chicken CDK6 Mammalian Cell His
    Zebrafish CDK6-7274Z Recombinant Zebrafish CDK6 Mammalian Cell His

    cdk6 involved in several pathways and played different roles in them. We selected most pathways cdk6 participated on our site, such as B Cell Receptor Signaling Pathway, C-MYB transcription factor network, Cell Cycle, which may be useful for your reference. Also, other proteins which involved in the same pathway with cdk6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    B Cell Receptor Signaling Pathway PTPN6; BANK1; BCL2L11; PRKCB; RAF1; CRK; IKBKB; AKT2; BLK; PPP3CA
    C-MYB transcription factor network SLC25A3; MYOD1; SMARCA2; PPID; PTCRA; CBX4; SKI; MYC; CREBBP; GATA1
    Cell Cycle PCNA; RBBP8; ORC6; TUBB4B; NUMA1; RAD9; PDS5B; CDC14A; GSK3B; GADD45B
    Cell Cycle, Mitotic DCTN2; OFD1; NDE1; TUBB4B; NDEL1; CEP152; GOLGA2; DCTN1; GMNN; GINS3
    Cellular Senescence TERF1; PHC2; PHC3; LMNB1; HIST1H1C; KAT5; RNF2; CDKN2D; CDK4; BMI1A
    Cellular responses to stress EP400; SUZ12; HIST2H3C; GABARAPL2; RBBP7; EGLN2; HIST1H1E; CBX6A; H3F3D; CDKN2C
    Chronic myeloid leukemia CBLB; MAP2K2; RAF1; TGFBR2; PIK3CD; PIK3R1; MAP2K1; SHC1; GAB2; PIK3R5

    cdk6 has several biochemical functions, for example, ATP binding, cyclin binding, cyclin-dependent protein serine/threonine kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cdk6 itself. We selected most functions cdk6 had, and list some proteins which have the same functions with cdk6. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding ADCK2; ABCG2D; CLP1; FANCM; P2RY1; PMS1; CKMT1; DDX25; CDC42BPB; CHD8
    cyclin binding MDFIC; PFTK1; CDK12; CDK2; CDK4; HDAC3; CDK5RAP3; CDKN1A; PTCH1; USP2
    cyclin-dependent protein serine/threonine kinase activity NAT1; CCNK; CDK1; CDK9; CDK15; CDK17; CDKL5; CDK2; CDK14; CDK19
    protein binding STOM; HINT2; FGFRL1B; TAL1; COPG; ATL2; LCP2; RPL39L; ZNHIT6; MST1R

    cdk6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdk6 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdk6.

    CDKN2A; CCND3

    Caro-Astorga, J; Fajardo, I; et al. Nascent histamine induces alpha-synuclein and caspase-3 on human cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 451:580-586(2014).
    Xu, F; Liu, J; et al. LSECtin Expressed on Melanoma Cells Promotes Tumor Progression by Inhibiting Antitumor T-cell Responses. CANCER RESEARCH 74:3418-3428(2014).

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