Recombinant Human CDK6 Protein, GST-Tagged
Cat.No. : | CDK6-1028H |
Product Overview : | Human CDK6 full-length ORF (AAH52264, 1 a.a. - 326 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 61.6 kDa |
AA Sequence : | MEKDGLCRADQQYECVAEIGEGAYG KVFKARDLKNGGRFVALKRVRVQTG EEGMPLSTIREVAVLRHLETFEHPN VVRLFDVCTVSRTDRETKLTLVFEH VDQDLTTYLDKVPEPGVPTETIKDM MFQLLRGLDFLHSHRVVHRDLKPQN ILVTSSGQIKLADFGLARIYSFQMA LTSVVVTLWYRAPEVLLQSSYATPV DLWSVGCIFAEMFRRKPLFRGSSDV DQLGKILDVIGLPGEEDWPRDVALP RQAFHSKSAQPIEKFVTDIDELGKD LLLKCLTFNPAKRISAYSALSHPYF QDLERCKENLDSHLPPSQNTSELNT A |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | CDK6 cyclin-dependent kinase 6 [ Homo sapiens ] |
Official Symbol : | CDK6 |
Synonyms : | CDK6; cyclin-dependent kinase 6; PLSTIRE; cell division protein kinase 6; serine/threonine-protein kinase PLSTIRE; MGC59692; |
Gene ID : | 1021 |
mRNA Refseq : | NM_001145306 |
Protein Refseq : | NP_001138778 |
MIM : | 603368 |
UniProt ID : | Q00534 |
Products Types
◆ Recombinant Protein | ||
CDK6-728H | Recombinant Human CDK6 Protein, His-tagged | +Inquiry |
CDK6/CCND1-277H | Recombinant Human CDK6/CCND1, His-tagged, GST-tagged, Active | +Inquiry |
CDK6-614R | Recombinant Rhesus Macaque CDK6 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDK6/CCND3-278H | Recombinant Human CDK6/CCND3, His-tagged, Active | +Inquiry |
CDK6-565H | Recombinant Human CDK6 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
CDK6-7622HCL | Recombinant Human CDK6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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