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CDKN2D

  • Official Full Name

    cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

  • Overview

    Cyclin-dependent kinase 4 inhibitor D (CDKN2D) is a specific inhibitor of cyclin-dependent kinases CDK4 and CDK6. CDK4 is a subunit of the protein kinase complex that is important for cell cycle G1 phase progression.
  • Synonyms

    CDKN2D; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); cyclin-dependent kinase 4 inhibitor D; INK4D; p19; CDK inhibitor p19INK4d; inhibitor of cyclin-dependent kinase 4d; cyclin-dependent kinase 4 inhibitor D p19; cell cycle inhibitor, Nur77 a;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CDKN2D-1254H Recombinant Human CDKN2D protein, His & T7-tagged E.coli His/T7 Met1~Leu166 (Accession # P55273)
Human CDKN2D-30050TH Recombinant Human CDKN2D E.coli N/A
Human CDKN2D-1476H Recombinant Human CDKN2D, GST-tagged E.coli GST
Human CDKN2D-2502H Active Recombinant Human CDKN2D protein(Met10-Leu166), GST-tagged E. coli N-GST Met10-Leu166
Human CDKN2D-33H Recombinant Human CDKN2D protein E.coli N/A 166aa
Human CDKN2D-1066H Recombinant Human CDKN2D Protein, GST-Tagged Wheat Germ GST
Human CDKN2D-7611HCL Recombinant Human CDKN2D 293 Cell Lysate HEK293 N/A
Human CDKN2D-7610HCL Recombinant Human CDKN2D 293 Cell Lysate HEK293 N/A
Human CDKN2D-1337H Recombinant Human CDKN2D Protein (Met1-Leu166), N-His tagged E.coli N-His Met1-Leu166
Human CDKN2D-3467H Recombinant Human CDKN2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CDKN2D-5118H Recombinant Human CDKN2D Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CDKN2D-570H-B Recombinant Human CDKN2D Protein Pre-coupled Magnetic Beads HEK293
Human CDKN2D-3233HF Recombinant Full Length Human CDKN2D Protein, GST-tagged In Vitro Cell Free System GST 166 amino acids
Human CDKN2D-721HFL Recombinant Full Length Human CDKN2D Protein, C-Flag-tagged Mammalian cells Flag
Human CDKN2D-570H Recombinant Human CDKN2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cdkn2d-1255M Recombinant Mouse Cdkn2d protein, His & T7-tagged E.coli His/T7 Met1~Met166 (Accession # Q60773)
Mouse Cdkn2d-872M Recombinant Mouse Cdkn2d Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rhesus Macaque CDKN2D-797R Recombinant Rhesus monkey CDKN2D Protein, His-tagged Mammalian Cell His
Rhesus Macaque CDKN2D-623R-B Recombinant Rhesus Macaque CDKN2D Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CDKN2D-623R Recombinant Rhesus Macaque CDKN2D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CDKN2D Related Articles
  • CDKN2D Related Research Area

CDKN2D involved in several pathways and played different roles in them. We selected most pathways CDKN2D participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Cellular Senescence, which may be useful for your reference. Also, other proteins which involved in the same pathway with CDKN2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleBRCC3;CENPQ;CUL1;GORASP1;ODF2;POT1;NINL;MCM6L;CDCA5
Cell Cycle, MitoticMASTL;CSNK1D;DSN1;RANGAP1B;CDK4;CENPC1;PCM1;CEP70;ESCO2
Cellular SenescenceMAPKAPK2B;CABIN1;E2F3;HIST1H1E;HIST1H1C;EED;TERF1;H3F3D;UBN1
Cellular responses to stressATG9A;HIF1AL;CBX4;DNAJC2;LAMTOR2;HIST1H1C;RRAGB;CBX6A;AGO3
Cyclin D associated events in G1CDKN2B;CDKN2D;PIANP;CKS1B;E2F4;CDKN2C;CDK7
FoxO signaling pathwayFBXO32;TGFBR1;KLF2;FOXG1A;IGF1R;SOD2;PCK2;MAP2K2;SLC2A4
G1 PhaseCDKN2B;E2F4;CKS1B;PIANP;CDKN2C;CDKN2D

CDKN2D has several biochemical functions, for example, cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CDKN2D itself. We selected most functions CDKN2D had, and list some proteins which have the same functions with CDKN2D. You can find most of the proteins on our site.

Function Related Protein
cyclin-dependent protein serine/threonine kinase inhibitor activityCDKN2B;INCA1;HEXIM1;KAT2B;CDKN2C;HEXIM2;CDKN1B;Casp3;CDKN1BA
protein bindingNPPA;DDX55;PRPF3;N6AMT1;LSM2;CDC37;PTPN18;PEBP1;COG1
protein kinase bindingSUFU;CALM3;DVL1;RAD9A;SKI;TSKS;CDC25B;NIPAL1;ADIPOR1

CDKN2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CDKN2D here. Most of them are supplied by our site. Hope this information will be useful for your research of CDKN2D.

CDK6; CDK4; C1orf94; IKZF3; NR4A2

Wang, Y; Jin, W; et al. Transcriptional repression of CDKN2D by PML/RAR alpha contributes to the altered proliferation and differentiation block of acute promyelocytic leukemia cells. CELL DEATH & DISEASE 5:-(2014).
Kannan, K; Coarfa, C; et al. CDKN2D-WDFY2 Is a Cancer-Specific Fusion Gene Recurrent in High-Grade Serous Ovarian Carcinoma. PLOS GENETICS 10:-(2014).
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