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Official Full Name cyclin-dependent kinase inhibitor 3
Background The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms CDKN3; cyclin-dependent kinase inhibitor 3; CDI1; CDK2 associated dual specificity phosphatase; cyclin dependent kinase inhibitor; KAP; kinase associated phosphatase; kinase-associated phosphatase; Cdk-associated protein phosphatase; cyclin-dependent kina
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CDKN3-1067H Recombinant Human CDKN3 Protein, GST-Tagged Wheat Germ GST
    Human CDKN3-2236H Recombinant Human CDKN3 Protein (1-212 aa), His-tagged Yeast His
    Human CDKN3-26470TH Recombinant Human CDKN3, His-tagged E.coli His
    Human CDKN3-26472TH Recombinant Human CDKN3 N/A
    Human CDKN3-599H Recombinant Human CDKN3 Protein, His/GST-tagged E.coli His/GST
    Human CDKN3-6980H Recombinant Human CDKN3, GST-tagged Sf9 Insect Cell GST
    Human CDKN3-700H Recombinant Human Cyclin-Dependent Kinase Inhibitor 3, GST-tagged E.coli GST
    Human CDKN3-7609HCL Recombinant Human CDKN3 293 Cell Lysate HEK293 N/A
    Human CDKN3-942H Recombinant Human Cyclin-Dependent Kinase Inhibitor 3, His-tagged E.coli His
    Mouse CDKN3-3229M Recombinant Mouse CDKN3 Protein Mammalian Cell His
    Rhesus Macaque CDKN3-798R Recombinant Rhesus monkey CDKN3 Protein, His-tagged Mammalian Cell His
    Chicken CDKN3-4556C Recombinant Chicken CDKN3 Mammalian Cell His
    Zebrafish CDKN3-7370Z Recombinant Zebrafish CDKN3 Mammalian Cell His

    cdkn3 involved in several pathways and played different roles in them. We selected most pathways cdkn3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with cdkn3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    cdkn3 has several biochemical functions, for example, protein binding, protein serine/threonine phosphatase activity, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by cdkn3 itself. We selected most functions cdkn3 had, and list some proteins which have the same functions with cdkn3. You can find most of the proteins on our site.

    Function Related Protein
    protein binding ZBTB49; PDIA6; MRPL10; TNPO2; INTS10; TSPYL4; VMP1; CBR4; HIST1H4H; PARN
    protein serine/threonine phosphatase activity PPP1R3D; PPP3CB; PPP2R1A; PPM1BA; PPM1NB; PPM1N; CTDNEP1; PPM1LB; PPA2; DULLARD
    protein tyrosine phosphatase activity MTMR7B; MTMR1A; EVLA; DUSP15; PTEN; DUSP5; MTMR6; PTPDC1; DUSP13; MTMR1
    protein tyrosine/serine/threonine phosphatase activity DUSP16; SSH3; MTMR2; NT5DC3; DUSP22B; DUSP15; DUSP19A; RNGTT; DUPD1; CTDSPL2B

    cdkn3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cdkn3 here. Most of them are supplied by our site. Hope this information will be useful for your research of cdkn3.

    CDK2; CDC28; CDK1; CDK3

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