cga
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  • Official Full Name
  • glycoprotein hormones, alpha polypeptide
  • Background
  • The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • CGA; glycoprotein hormones, alpha polypeptide; HCG; LHA; FSHA; GPHa; TSHA; GPHA1; CG-ALPHA; glycoprotein hormones alpha chain; FSH-alpha; LSH-alpha; TSH-alpha; lutropin alpha chain; follitropin alpha chain; thyrotropin alpha chain; choriogonadotropin alph
Cat.#:CGA-452HTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CGA Protein (Met1-Ser116)
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Cat.#:CGA-1182HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CGA Protein, GST-Tagged
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Cat.#:CGA-109HTag:N/A
Source (Host):CHOSpecies:Human
Product nameRecombinant Human Glycoprotein Hormones, Alpha Polypeptide
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Cat.#:CGA-224HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human CGA, StrepII-tagged
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Cat.#:CGA-285HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human CGA, Fc-tagged
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Cat.#:CGA-286HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human CGA, His-tagged
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Cat.#:CGA-49HTag:
Source (Host):YeastSpecies:Human
Product nameRecombinant Human CGA
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Cat.#:CGA-7786HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CGA protein, His & GST-tagged
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Cat.#:Cga-7787MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Cga protein, His-tagged
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Cat.#:CGA-404CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CGA Protein, His-tagged
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Cat.#:CGA-5303CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CGA
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Cat.#:CGA-11710ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CGA
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Cat.#:CGA-1855HTag:N/A
Source (Host):Human Pregnancy UrineSpecies:Human
Product nameNative Human, Glycoprotein Hormones, Alpha Polypeptide
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Cat.#:CGA-8162HTag:N/A
Source (Host):Human Pregnancy UrineSpecies:Human
Product nameNative Human Pregnancy Chorionic Gonadotropin
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Cat.#:CGA-8163HTag:N/A
Source (Host):Human Pregnancy UrineSpecies:Human
Product nameNative Human Chorionic Gonadotropin
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Cat.#:CGA-8356HTag:
Source (Host):UrineSpecies:Human
Product nameNative Human CGA
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Cat.#:CGA-001HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human CGA cell lysate
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Involved Pathway

CGA involved in several pathways and played different roles in them. We selected most pathways CGA participated on our site, such as Amine-derived hormones, Androgen biosynthesis, Autoimmune thyroid disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with CGA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Amine-derived hormones
CGA; DDC; DIO2; DBH; TPH2
Androgen biosynthesis
PPP1R2; CGA; POMCB; CYP17A1
Autoimmune thyroid disease
CGA; CTLA4; OSTN; IFN-a; IL10
Class A/1 (Rhodopsin-like receptors)
TAC3; CXCR7B; EDN1; GPR39; ADRB3; SSTR2; CCBP2; PMCH; KEL; EDNRAB
FSH signaling pathway
CGA; CYP19A1; AREG
G alpha (s) signalling events
NPSR1; CRHR2; GCGA; RLN3; ADM; CALCA; ADM2A; PDE10A; GPBAR1; ADCYAP1
GPCR downstream signaling
GNA13B; CCR9; TAAR1; GPR132; OXGR1; HCRT; APLNR; OPN1MW; VIP; ARHGEF9
GPCR ligand binding
CRHR2; LPAR2B; EDNRA; GPR77; XK; CCR1; CALCA; OPN1SW; GPR55A; NMS

Protein Function

CGA has several biochemical functions, for example, hormone activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CGA itself. We selected most functions CGA had, and list some proteins which have the same functions with CGA. You can find most of the proteins on our site.
Function
Related Protein
Function hormone activity
Related Protein PRL7B1; POMCB; FNDC5B; C19orf80; POMCA; SST2; EPO; PRL8A8; TTR; C1QTNF9
Function protein binding
Related Protein PCDHA4; CPSF7; CDK6; JAG2; STAG1; PRICKLE1A; ILF3; MPZL2B; APOBEC3C; CHRNA5

Interacting Protein

CGA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CGA here. Most of them are supplied by our site. Hope this information will be useful for your research of CGA.
FSHB; CGB; PTN; PTPN12

CGA Related Articles

Glinicki, P; Jeske, W; et al. Comparison of chromogranin A (CgA) levels in serum and plasma (EDTA(2)K) and the respective reference ranges in healthy males. ENDOKRYNOLOGIA POLSKA 66:53-56(2015).
Ramirez, GA; Rodriguez, F; et al. Morphologic and immunohistochemical features of Merkel cells in the dog. RESEARCH IN VETERINARY SCIENCE 97:475-480(2014).