CHST13

  • Official Full Name

    carbohydrate (chondroitin 4) sulfotransferase 13

  • Overview

    The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.
  • Synonyms

    CHST13; carbohydrate (chondroitin 4) sulfotransferase 13; carbohydrate sulfotransferase 13; C4ST3; C4ST 3; C4ST-3; Chondroitin 4 O sulfotransferase 3; Chondroitin 4 sulfotransferase 3; Chondroitin 4-O-sulfotransferase 3; Chondroitin 4-sulfotransferase 3; CHST 13; CHSTD_HUMAN; MGC119278; MGC119279; MGC119281;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHST13-11226H Recombinant Human CHST13, His-tagged E.coli His 1-110a.a.
Human CHST13-1340H Recombinant Human CHST13 Protein, GST-tagged Wheat Germ GST
Human CHST13-354HCL Recombinant Human CHST13 cell lysate N/A
Human CHST13-1830HF Recombinant Full Length Human CHST13 Protein, GST-tagged In Vitro Cell Free System GST 225 amino acids
Rhesus Macaque CHST13-868R Recombinant Rhesus monkey CHST13 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CHST13-694R Recombinant Rhesus Macaque CHST13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CHST13-694R-B Recombinant Rhesus Macaque CHST13 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CHST13 involved in several pathways and played different roles in them. We selected most pathways CHST13 participated on our site, such as Activated TLR4 signalling, Cytosolic sensors of pathogen-associated DNA, DEx/H-box helicases activate type I IFN and inflammatory cytokines production, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activated TLR4 signallingAGER;MAPKAPK2B;PELI1;JUN;DUSP6;CREB1B;TICAM1;S100B;DUSP3
Cytosolic sensors of pathogen-associated DNADDX41;CRCP;TREX1;POLR3GLA;POLR3F;LRRFIP1;NLRP4B;APPA;DHX9
DEx/H-box helicases activate type I IFN and inflammatory cytokines productionALCAMB;APPA;S100B;AGER;APPB;SAA1;CHST13;DHX9;S100A12
Gene ExpressionZNF740;ZNF561;RNPC3;EEF1B2;ZNF599;WDR4;ZNF317;LAMTOR1;ZNF701
Immune SystemCYLD;MKRN1;KLC3;S100A12;MGC174155;PJA2;KIF22;HCST;DEFB106A
Innate Immune SystemUNC93B1;BTR02;NLRP4C;IFI16;LY86;MASP2;POLR3H;FAM49BA;WASF3
MyD88 cascade initiated on plasma membraneTLR10;AGER;CHST13;TNIP2;PELI3;DUSP3B;DHX9;S100A12;S100B
MyD88 dependent cascade initiated on endosomeS100B;S100A12;CHST13;ALCAMB;DHX9

CHST13 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST13 itself. We selected most functions CHST13 had, and list some proteins which have the same functions with CHST13. You can find most of the proteins on our site.

Function Related Protein
ATP bindingGPHN;PIK3R4;RPS6KA6;TSSK2;SLC22A5;CHD8;YME1L1B;SRPK1A;P2RX5
ATP-dependent DNA helicase activityRECQL;RTEL1;BLM;FBXO18;DDX11;CHD4;XRCC5;ERCC3;GTF2H4
ATP-dependent RNA helicase activityDDX43;DDX18;DDX19;DDX47;SUPV3L1;DDX4;DDX55;DDX46;EIF4A1
DNA bindingArid4b;H2AFJ;GTF2A1;NR5A2;H2AFY;MKXB;ZFP553;ESRRGB;PROX1A
RNA helicase activityDDX10;PRIM2;DHX15;DHX9;UAP1L1;CTU1;DDX6;FAM120B;DDX24
RNA polymerase II transcription factor bindingGATA2A;GFI1B;GATA2;GATA4;CREBBP;TRPS1;TRP53;MEF2A;SMAD4
poly(A) RNA bindingMRPL39;HNRPLL;METTL16;PUM2;CLK3;NDUFV3;POP7;LARP1;CISD2
protein bindingFSHR;KIAA1143;FUS;CLCF1;PLA2G16;TAF12;KDRL;PSMB4;NR2F6

CHST13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST13.

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