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CHST13

Official Full Name

carbohydrate (chondroitin 4) sulfotransferase 13
Overview

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.
Synonyms

CHST13; carbohydrate (chondroitin 4) sulfotransferase 13; carbohydrate sulfotransferase 13; C4ST3; C4ST 3; C4ST-3; Chondroitin 4 O sulfotransferase 3; Chondroitin 4 sulfotransferase 3; Chondroitin 4-O-sulfotransferase 3; Chondroitin 4-sulfotransferase 3; CHST 13; CHSTD_HUMAN; MGC119278; MGC119279; MGC119281;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rhesus Macaque

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	CHST13-11226H	Recombinant Human CHST13, His-tagged	E.coli	His	1-110a.a.	$319 / 25ug
Human	CHST13-1340H	Recombinant Human CHST13 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	CHST13-354HCL	Recombinant Human CHST13 cell lysate		N/A		Inquiry
Human	CHST13-1830HF	Recombinant Full Length Human CHST13 Protein, GST-tagged	In Vitro Cell Free System	GST	225 amino acids	Inquiry
Rhesus Macaque	CHST13-868R	Recombinant Rhesus monkey CHST13 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	CHST13-694R	Recombinant Rhesus Macaque CHST13 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	CHST13-694R-B	Recombinant Rhesus Macaque CHST13 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

CHST13 involved in several pathways and played different roles in them. We selected most pathways CHST13 participated on our site, such as Activated TLR4 signalling, Cytosolic sensors of pathogen-associated DNA, DEx/H-box helicases activate type I IFN and inflammatory cytokines production, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Activated TLR4 signalling	AGER;MAPKAPK2B;PELI1;JUN;DUSP6;CREB1B;TICAM1;S100B;DUSP3
Cytosolic sensors of pathogen-associated DNA	DDX41;CRCP;TREX1;POLR3GLA;POLR3F;LRRFIP1;NLRP4B;APPA;DHX9
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	ALCAMB;APPA;S100B;AGER;APPB;SAA1;CHST13;DHX9;S100A12
Gene Expression	ZNF740;ZNF561;RNPC3;EEF1B2;ZNF599;WDR4;ZNF317;LAMTOR1;ZNF701
Immune System	CYLD;MKRN1;KLC3;S100A12;MGC174155;PJA2;KIF22;HCST;DEFB106A
Innate Immune System	UNC93B1;BTR02;NLRP4C;IFI16;LY86;MASP2;POLR3H;FAM49BA;WASF3
MyD88 cascade initiated on plasma membrane	TLR10;AGER;CHST13;TNIP2;PELI3;DUSP3B;DHX9;S100A12;S100B
MyD88 dependent cascade initiated on endosome	S100B;S100A12;CHST13;ALCAMB;DHX9

CHST13 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST13 itself. We selected most functions CHST13 had, and list some proteins which have the same functions with CHST13. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	GPHN;PIK3R4;RPS6KA6;TSSK2;SLC22A5;CHD8;YME1L1B;SRPK1A;P2RX5
ATP-dependent DNA helicase activity	RECQL;RTEL1;BLM;FBXO18;DDX11;CHD4;XRCC5;ERCC3;GTF2H4
ATP-dependent RNA helicase activity	DDX43;DDX18;DDX19;DDX47;SUPV3L1;DDX4;DDX55;DDX46;EIF4A1
DNA binding	Arid4b;H2AFJ;GTF2A1;NR5A2;H2AFY;MKXB;ZFP553;ESRRGB;PROX1A
RNA helicase activity	DDX10;PRIM2;DHX15;DHX9;UAP1L1;CTU1;DDX6;FAM120B;DDX24
RNA polymerase II transcription factor binding	GATA2A;GFI1B;GATA2;GATA4;CREBBP;TRPS1;TRP53;MEF2A;SMAD4
poly(A) RNA binding	MRPL39;HNRPLL;METTL16;PUM2;CLK3;NDUFV3;POP7;LARP1;CISD2
protein binding	FSHR;KIAA1143;FUS;CLCF1;PLA2G16;TAF12;KDRL;PSMB4;NR2F6

CHST13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST13.