CHST13
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Official Full Name
carbohydrate (chondroitin 4) sulfotransferase 13
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Overview
The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. -
Synonyms
CHST13; carbohydrate (chondroitin 4) sulfotransferase 13; carbohydrate sulfotransferase 13; C4ST3; C4ST 3; C4ST-3; Chondroitin 4 O sulfotransferase 3; Chondroitin 4 sulfotransferase 3; Chondroitin 4-O-sulfotransferase 3; Chondroitin 4-sulfotransferase 3; CHST 13; CHSTD_HUMAN; MGC119278; MGC119279; MGC119281;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Rhesus Macaque
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- Fc
- Avi
- Non
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | CHST13-11226H | Recombinant Human CHST13, His-tagged | E.coli | His | 1-110a.a. | |
| Human | CHST13-1340H | Recombinant Human CHST13 Protein, GST-tagged | Wheat Germ | GST |
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| Human | CHST13-354HCL | Recombinant Human CHST13 cell lysate | Non |
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| Human | CHST13-1830HF | Recombinant Full Length Human CHST13 Protein, GST-tagged | In Vitro Cell Free System | GST | 225 amino acids |
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| Rhesus Macaque | CHST13-868R | Recombinant Rhesus monkey CHST13 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | CHST13-694R | Recombinant Rhesus Macaque CHST13 Protein, His (Fc)-Avi-tagged | HEK293 | His&Fc&Avi |
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| Rhesus Macaque | CHST13-694R-B | Recombinant Rhesus Macaque CHST13 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
CHST13 involved in several pathways and played different roles in them. We selected most pathways CHST13 participated on our site, such as Activated TLR4 signalling, Cytosolic sensors of pathogen-associated DNA, DEx/H-box helicases activate type I IFN and inflammatory cytokines production, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Activated TLR4 signalling | JUN;CREB1;DUSP6;PELI2;S100A12;IRAK3;AGER;DUSP3B;ALCAMB |
| Cytosolic sensors of pathogen-associated DNA | APPA;IFI16;NLRP4;APPB;POLR3H;CHST13;RIPK3;NLRP4C;POLR3G |
| DEx/H-box helicases activate type I IFN and inflammatory cytokines production | S100A12;APPB;DHX9;CHST13;ALCAMB;AGER;SAA1;S100B;APPA |
| Gene Expression | PTBP1A;ZNF143;TSEN34;TRDMT1;ZNF485;GTF3AB;ZNF285A;TET2;MED13A |
| Immune System | UBE2J2;DEFB119;ASB18;CASP2;RNF138;WASF3;TRAF7;TXNIPB;PELI2 |
| Innate Immune System | TXNIPA;NLRP4C;Txn1;ABI1A;FCN1;ACTR2B;HERC5;DEFB129;DEFB4A |
| MyD88 cascade initiated on plasma membrane | DUSP3B;DHX9;PELI2;ALCAMB;TNIP2;CHST13;AGER;TLR10;PELI1 |
| MyD88 dependent cascade initiated on endosome | CHST13;DHX9;S100B;S100A12;ALCAMB |
CHST13 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST13 itself. We selected most functions CHST13 had, and list some proteins which have the same functions with CHST13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | RAD51C;DCLK1;RPS6KC1;MAP3K5;SIK2;CDC34;ACTA1B;GALK2;ERBB4 |
| ATP-dependent DNA helicase activity | ERCC3;CHST13;BRIP1;DDX11;RUVBL2;DDX3X;WRN;CHD4;FBXO18 |
| ATP-dependent RNA helicase activity | DDX23;DDX43;DDX3Y;EIF4A1B;DHX57;EIF4A3;EIF4A2;DDX4;DQX1 |
| DNA binding | CAMTA1;APEX2;MYO18A;YBX2;NFRKB;ZNF776;GTF2F2;ZFP335;NFE2L1B |
| RNA helicase activity | DHX15;CHST13;CCDC111;DDX17;DHX9;DDX6;SKIV2L2;CTU1;DHX16 |
| RNA polymerase II transcription factor binding | TAL1;TEAD3;GATA2B;KDM1A;ATF4;MEF2A;TBX3;SPI1;CHST13 |
| poly(A) RNA binding | RPL22;CHD2;CCDC124;CNBP;RPF2;DIAPH1;RPS27.1;MRPS7;PPIB |
| protein binding | MAT2B;SNIP1;IL5;CTBP1;HDAC9;ACAP1;CSTF1;ITGB7;PPIB |
CHST13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST13.
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