• Official Full Name

    carbohydrate (chondroitin 4) sulfotransferase 13

  • Background

    The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to the C4 hydroxyl of beta-1,4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.
  • Synonyms

    CHST13; carbohydrate (chondroitin 4) sulfotransferase 13; carbohydrate sulfotransferase 13; C4ST3; C4ST 3; C4ST-3; Chondroitin 4 O sulfotransferase 3; Chondroitin 4 sulfotransferase 3; Chondroitin 4-O-sulfotransferase 3; Chondroitin 4-sulfotransferase 3; CHST 13; CHSTD_HUMAN; MGC119278; MGC119279; MGC119281;
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • In Vitro Cell Free System
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • His (Fc)
    • Avi
    • N/A
    Species Cat.# Product name Source (Host) Tag Price
    Human CHST13-11226H Recombinant Human CHST13, His-tagged E.coli His
    Human CHST13-1340H Recombinant Human CHST13 Protein, GST-tagged Wheat Germ GST
    Human CHST13-354HCL Recombinant Human CHST13 cell lysate N/A
    Human CHST13-1830HF Recombinant Full Length Human CHST13 Protein, GST-tagged In Vitro Cell Free System GST
    Rhesus Macaque CHST13-868R Recombinant Rhesus monkey CHST13 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CHST13-694R Recombinant Rhesus Macaque CHST13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus Macaque CHST13-694R-B Recombinant Rhesus Macaque CHST13 Protein Pre-coupled Magnetic Beads HEK293
    • Involved Pathway
    • Protein Function
    • Interacting Protein

    CHST13 involved in several pathways and played different roles in them. We selected most pathways CHST13 participated on our site, such as Activated TLR4 signalling, Cytosolic sensors of pathogen-associated DNA, DEx/H-box helicases activate type I IFN and inflammatory cytokines production, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Activated TLR4 signallingTANK;AGER;SIGIRR;DHX9;DUSP4;DUSP7;TICAM1;S100B;MAPK14
    Cytosolic sensors of pathogen-associated DNANLRP4E;ALCAMB;NLRP4C;S100A12;TREX1;DDX41;NLRP4B;SAA1;POLR3H
    DEx/H-box helicases activate type I IFN and inflammatory cytokines productionS100A12;S100B;CHST13;SAA1;APPB;APPA;ALCAMB;DHX9;AGER
    Gene ExpressionRNF111;METTL14;SNRNP25;NR6A1;CSTF1;ZNF75D;EFCAB11;COX5B;ZNF740
    MyD88 cascade initiated on plasma membraneS100B;PELI1;AGER;DHX9;S100A12;PELI2;DUSP3B;ALCAMB;PELI3
    MyD88 dependent cascade initiated on endosomeDHX9;S100A12;S100B;CHST13;ALCAMB

    CHST13 has several biochemical functions, for example, ATP binding, ATP-dependent DNA helicase activity, ATP-dependent RNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST13 itself. We selected most functions CHST13 had, and list some proteins which have the same functions with CHST13. You can find most of the proteins on our site.

    Function Related Protein
    ATP-dependent DNA helicase activityXRCC5;BRIP1;XRCC6;ERCC3;RUVBL2;RECQL;GTF2H4;CHD1;FBXO18
    ATP-dependent RNA helicase activityDDX47;EIF4A1;DDX50;CHST13;DHX34;DHX57;TMEM38A;DDX39AA;DDX42
    RNA helicase activitySKIV2L2;CTU1;CCDC111;UAP1L1;RAD54B;PRIM2;DHX16;DHX9;DDX17
    RNA polymerase II transcription factor bindingGFI1B;DHX9;GATA2B;ZFPM2A;T;GATA2;MIXL1;XBP1;TRPS1
    poly(A) RNA bindingC14orf21;TNRC6B;EIF3E;UBE2L3;NOL10;SAP18;RRP9;HDGF;RBM15B
    protein bindingCYTH1;KRT38;CAPN1;STK24;UBE2F;UBE2D3;NETO2;REL;SPRY4

    CHST13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST13 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST13.

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