CHST4 Protein


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Official Full Name carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
Background This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3phosphoadenosine 5phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5 UTR results in multiple transcript variants that encode the same protein.
Synonyms CHST4; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4; carbohydrate sulfotransferase 4; HEC GLCNAC 6 ST; LSST; Carbohydrate (N acetylglucosamine 6-O) sulfotransferase 4; Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 3; GlcNAc6ST 2; GST 3; HEC GlcNAc6ST; High endothelial cells N acetylglucosamine 6 O sulfotransferase; L selectin ligand sulfotransferase; N acetylglucosamine 6 O sulfotransferase; GST-3; gn6st-2; glcNAc6ST-2; HEC-GlcNAc6ST; OTTHUMP00000174926; L-selectin ligand sulfotransferase; N-acetylglucosamine 6-O-sulfotransferase 2; high endothelial cells N-acetylglucosamine 6-O-sulfotransferase; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; galactose/N-acetylglucosamine/N-acetylgalactosamine 6-O-sulfotransferase 3; GST3; GlcNAc6ST2; HECGLCNAC6ST
    • Species :
    • Human
    • Mouse
    • Source :
    • CHO
    • E.coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CHST4-3227H Recombinant Human CHST4 protein, His-tagged E.coli His
    Human CHST4-11230H Recombinant Human CHST4, His-tagged E.coli His
    Human CHST4-1344H Recombinant Human CHST4 Protein, GST-tagged Wheat Germ GST
    Human CHST4-561H Recombinant Human CHST4 Protein, His-tagged CHO His
    Mouse CHST4-3453M Recombinant Mouse CHST4 Protein Mammalian Cell His

    CHST4 involved in several pathways and played different roles in them. We selected most pathways CHST4 participated on our site, such as Glycosaminoglycan biosynthesis - keratan sulfate, metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycosaminoglycan biosynthesis - keratan sulfate ST3GAL3; FUT8; ST3GAL1; CHST1; B3GNT2B; B4GALT1; FUT8A; CHST2; B3GNT7; B3GNT2
    metapathway biotransformation SULT1C2; NAA20; KCNAB1; CHST8; CYP4Z1; KCNAB2; NAT8B; CHST9; SULT1C4; SULT4A1

    CHST4 has several biochemical functions, for example, N-acetylglucosamine 6-O-sulfotransferase activity, sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST4 itself. We selected most functions CHST4 had, and list some proteins which have the same functions with CHST4. You can find most of the proteins on our site.

    Function Related Protein
    N-acetylglucosamine 6-O-sulfotransferase activity HS3ST3B1B; SULT5A1; SULT1ST7; CHST4; CHST3; GAL3ST3; Sult3a1; HS6ST1B; CHST2A; SULT1ST3
    sulfotransferase activity SULT3ST3; SULT2ST3; UST; SULT3ST2; SULT1ST4; HS3ST1; CHST1; HS3ST1L2; HS6ST1B; SULT1ST2

    CHST4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST4.


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