CHST4

  • Official Full Name

    carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

  • Overview

    This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3phosphoadenosine 5phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5 UTR results in multiple transcript variants that encode the same protein.
  • Synonyms

    CHST4; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4; carbohydrate sulfotransferase 4; HEC GLCNAC 6 ST; LSST; Carbohydrate (N acetylglucosamine 6-O) sulfotransferase 4; Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 3; GlcNAc6ST 2; GST 3; HEC GlcNAc6ST; High endothelial cells N acetylglucosamine 6 O sulfotransferase; L selectin ligand sulfotransferase; N acetylglucosamine 6 O sulfotransferase; GST-3; gn6st-2; glcNAc6ST-2; HEC-GlcNAc6ST; OTTHUMP00000174926; L-selectin ligand sulfotransferase; N-acetylglucosamine 6-O-sulfotransferase 2; high endothelial cells N-acetylglucosamine 6-O-sulfotransferase; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 3; galactose/N-acetylglucosamine/N-acetylgalactosamine 6-O-sulfotransferase 3; GST3; GlcNAc6ST2; HECGLCNAC6ST;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • CHO
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CHST4-561H Active Recombinant Human CHST4 Protein, His-tagged CHO His His29-His386
Human CHST4-11230H Recombinant Human CHST4, His-tagged E.coli His C-term-310a.a.
Human CHST4-1344H Recombinant Human CHST4 Protein, GST-tagged Wheat Germ GST
Human CHST4-3227H Recombinant Human CHST4 protein, His-tagged E.coli His 177-386 aa
Human CHST4-1835HF Recombinant Full Length Human CHST4 Protein, GST-tagged In Vitro Cell Free System GST 370 amino acids
Mouse CHST4-3453M Recombinant Mouse CHST4 Protein Mammalian Cell His
Mouse CHST4-1676M-B Recombinant Mouse CHST4 Protein Pre-coupled Magnetic Beads HEK293
Mouse CHST4-1676M Recombinant Mouse CHST4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein

CHST4 involved in several pathways and played different roles in them. We selected most pathways CHST4 participated on our site, such as Glycosaminoglycan biosynthesis - keratan sulfate, metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with CHST4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycosaminoglycan biosynthesis - keratan sulfateB3GNT7;Chst5;B4GALT1;B4GALT2;B4GALT4;B4GALT3;B3GNT2B;CHST4;B3GNT2
metapathway biotransformationGAL3ST3;NAT8B;SULT1C4;KCNAB2;PRKRA;CHST8;CEACAM21;NAA40;NAT8

CHST4 has several biochemical functions, for example, N-acetylglucosamine 6-O-sulfotransferase activity, sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CHST4 itself. We selected most functions CHST4 had, and list some proteins which have the same functions with CHST4. You can find most of the proteins on our site.

Function Related Protein
N-acetylglucosamine 6-O-sulfotransferase activityCHST2A;SULT1ST4;SULT1D1;HS3ST3L;HS6ST1A;SULT1ST3;SULT2ST2;GAL3ST3;CHST3
sulfotransferase activitySULT3ST4;SULT1A2;DSEL;SULT3ST2;SULT1ST3;Sult2a6;SULT1D1;SULT1C2;SULT4A1

CHST4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CHST4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CHST4.

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