CMPK2
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Official Full Name
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial -
Overview
This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal;differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this;gene. -
Synonyms
CMPK2;cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial;UMP-CMP kinase 2, mitochondrial;cytidylate kinase 2;TYKi;UMP CMPK2;UMP CMP kinase 2, mitochondrial;1200004E04Rik;Cytidine monophosphate (UMP CMP) kinase 2, mitochondrial;Mitochondrial UMP CMP kinase;OTTHUMP00000200305;Thymidine monophosphate kinase 2;TMPK2;mitochondrial UMP-CMP kinase;thymidylate kinase family LPS-inducible member;UMP-CMPK2
Recombinant Proteins
- Human
- Mouse
- HEK293
- Mammalian Cells
- Wheat Germ
- Avi
- Fc
- His
- GST
- Flag
- DDK
- Myc
Involved Pathway
CMPK2 involved in several pathways and played different roles in them. We selected most pathways CMPK2 participated on our site, such as CMP phosphorylation,Metabolic pathways,Pyrimidine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with CMPK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| CMP phosphorylation | NME6 |
| Metabolic pathways | CRYL1,PLA2G2D,ALOX12B,DHFRL1,ATP5I,APIP,GGT6,HSD3B6,CMBL,PTGES3A |
| pyrimidine deoxyribonucleotide phosphorylation | DTYMK |
| Pyrimidine metabolism | NUDT2,TK2,POLR1A,POLR2J3,POLR1D,POLE4,NME5,NT5C2A,DPYS,POLR1E |
| UTP and CTP de novo biosynthesis | NME6 |
| superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis | DUT |
Protein Function
CMPK2 has several biochemical functions, for example, ATP binding,UMP kinase activity,cytidylate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CMPK2 itself. We selected most functions CMPK2 had, and list some proteins which have the same functions with CMPK2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cytidylate kinase activity | CMPK,AK7,CMPK1,AK8 |
| ATP binding | LANCL2,H1FNT,EHD1,FPGS,PRKD2,CHKA,CAMK2D2,PEX1,KARS,SUCLG2 |
| thymidylate kinase activity | DTYMK |
| nucleoside diphosphate kinase activity | AK8,NME2B.2,AK1,NME5,NME4,CMPK1,AK7,AK5,TXNDC3,NME2B.1 |
Interacting Protein
CMPK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CMPK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of CMPK2.
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