CMTM4
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Official Full Name
CKLF-like MARVEL transmembrane domain containing 4
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Overview
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
CMTM4; CKLF-like MARVEL transmembrane domain containing 4; chemokine like factor super family 4 , chemokine like factor superfamily 4 , CKLFSF4; CKLF-like MARVEL transmembrane domain-containing protein 4; Chemokine-like factor superfamily member 4; CKLF4; CKLFSF4; OTTHUMP00000174785; chemokine-like factor super family 4;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Zebrafish
- E.coli expression system
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mamanlian cells
- Mammalian Cell
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- Involved Pathway
- Protein Function
- Interacting Protein
CMTM4 involved in several pathways and played different roles in them. We selected most pathways CMTM4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with CMTM4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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CMTM4 has several biochemical functions, for example, cytokine activity, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by CMTM4 itself. We selected most functions CMTM4 had, and list some proteins which have the same functions with CMTM4. You can find most of the proteins on our site.
Function | Related Protein |
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cytokine activity | IL9;Ccl9;CMTM1;WNT5A;IFNL3;TGFB3;TNFSF14;Il1f8;TNFSF8 |
molecular_function | STOML3B;SHISA6;D19WSU162E;C14orf2;CCDC15;FBXO36A;CRP7;CLHC1;HIP1RA |
CMTM4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CMTM4 here. Most of them are supplied by our site. Hope this information will be useful for your research of CMTM4.
- Q&As
- Reviews
Q&As (5)
Ask a questionAltered expression of CMTM4 protein has been associated with disease progression in certain cancers, indicating its potential as a prognostic marker for these diseases.
CMTM4 protein has been shown to enhance T cell activation and effector functions, suggesting its role in modulating immune responses against cancer and infections.
Researchers are exploring the possibility of targeting CMTM4 protein to modulate immune responses and potentially develop new therapeutic interventions for cancer and autoimmune diseases.
Dysregulation of CMTM4 protein expression has been linked to autoimmune diseases, highlighting its potential as a target for developing new treatments for these conditions.
CMTM4 protein interacts with and modulates the activity of immune checkpoint molecules, influencing the function of immune cells and their responses to tumors and pathogens.
Customer Reviews (3)
Write a reviewThe CMTM4 protein comes highly recommended for a variety of applications, particularly in ELISA and protein electron microscopy structure analysis.
Researchers can rely on the CMTM4 protein's specificity and sensitivity to obtain accurate and reliable results.
researchers highly recommend the CMTM4 protein due to its excellent performance in ELISA and its suitability for protein electron microscopy structure analysis.
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