|Official Full Name||CCR4-NOT transcription complex, subunit 4|
|Background||The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||CNOT4; CCR4-NOT transcription complex, subunit 4; NOT4; CCR4-NOT transcription complex subunit 4; CLONE243; NOT4H; CCR4-associated factor 4; E3 ubiquitin-protein ligase CNOT4; potential transcriptional repressor NOT4Hp; NOT4 (negative regulator of transcr|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cnot4 involved in several pathways and played different roles in them. We selected most pathways cnot4 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with cnot4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|RNA degradation||LSM8; PABPC1L; PFKM; LSM6; TOB1A; ZCCHC7; DnaK; CNOT3A; PABPC1; PABPC1B|
cnot4 has several biochemical functions, for example, ligase activity, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cnot4 itself. We selected most functions cnot4 had, and list some proteins which have the same functions with cnot4. You can find most of the proteins on our site.
|ligase activity||RFFL; RANBP2; KCNG4; UBR1; RNF126; DZIP3; TRIML1; COP1; ACSL1; RNF181|
|nucleotide binding||CPEB1A; TDRD9; MAP2K4B; RAB1BB; PUF60A; RDBP; UBE1Y1; EPHA4A; DHX33; TUBA1L2|
|poly(A) RNA binding||AKAP17A; TIAL1; PRR3; RTCA; EEF1A1; NOVA1; FAM32A; PPRC1; PRKDC; SUGP2|
|protein binding||C1orf105; ZFPM2; RAN; ADAMTS3; CORO1B; SKAP2; HAUS1; POP1; APPB; MPP2|
|ubiquitin-protein transferase activity||UBE2D4; UBE2R2; RNF4; ANAPC4; MARCH1; UBR3; FEM1B; RNF146; TRAF2; CDC34|
|zinc ion binding||NEURL1AA; RNF215; ADAM10; FBXO40; RORCB; PMPCB; ZDHHC20; CA15A; CPSF4; CPA1|
cnot4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cnot4 here. Most of them are supplied by our site. Hope this information will be useful for your research of cnot4.
UBE2D3; UBE2N; UBE2D2; EP300; UBE2E3; UBE2W; UBE2D4; MYC