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COL4A1

  • Official Full Name

    collagen, type IV, alpha 1

  • Synonyms

    COL4A1; collagen, type IV, alpha 1; collagen alpha-1(IV) chain; COL4A1 NC1 domain; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain; HANAC; POREN1; arresten;

  • Recombinant Proteins
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cattle
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Mammalian Cell
  • Placenta
  • GST
  • His
  • His (Fc)
  • Avi
  • His|S
  • SUMO
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human COL4A1-611H Recombinant Human COL4A1 protein, His & S-tagged E.coli His/S His1444~Thr1669 (Accession # P02462)
Human COL4A1-5269H Recombinant Human COL4A1 protein, GST-tagged E.coli GST 30-167aa
Human COL4A1-1764H Recombinant Human COL4A1 Protein (His1444-Thr1669), N-His tagged E.coli N-His His1444-Thr1669
Human COL4A1-001H Native Human COL4A1 Protein Placenta
Human COL4A1-2713H Recombinant Human COL4A1 protein, His-SUMO-tagged E.coli His-SUMO 1445-1669aa
Mouse COL4A1-3735M Recombinant Mouse COL4A1 Protein Mammalian Cell His
Mouse COL4A1-1863M Recombinant Mouse COL4A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Col4a1-820M Recombinant Mouse Col4a1 Protein, His-tagged E.coli N-His Pro1416-Thr1669
Mouse COL4A1-1863M-B Recombinant Mouse COL4A1 Protein Pre-coupled Magnetic Beads HEK293
Cattle COL4A1-819C Recombinant Cattle COL4A1 Protein, His-tagged E.coli N-His Gly1445-Thr1669
Chicken COL4A1-3967C Recombinant Chicken COL4A1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • COL4A1 Related Articles
  • COL4A1 Related Research Area

COL4A1 involved in several pathways and played different roles in them. We selected most pathways COL4A1 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL4A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PIK-Akt signaling pathwayPPP2R2B;FGF22;MAP2K1;PPP2R3A;MET;LAMC1;SPP1;TNXB;TCL1B4
Focal adhesionPAK2B;PIK3R3B;PIK3CD;ACTN2;COL6A4;TNK2;ITGB7;GSK3AA;RAPGEF1
ECM-receptor interactionITGA6;CD36;COL2A1B;HMMR;ITGA11A;ITGB3B;GP1BB;COL6A6;COL6A1
Protein digestion and absorptionATP1A1;CELA2A;SLC8A1;COL10A1;ATP1A4;KCNK5;DPP4;CELA3B;PRSS1
AmoebiasisRAB7;IL1B;COL1A2;LAMA5;PIK3CD;Casp3;LAMB1;IL12A;PLCB4
Pathways in cancerWNT16;PML;GNAQ;MECOM;MSH3;GRB2;PIK3CB;TFG;TRAF4
Small cell lung cancerPTGS2;NOS2;CCNE1;PIK3R5;NFKBIA;CCNE2;PTEN;BIRC8;PIK3CA

COL4A1 has several biochemical functions, for example, extracellular matrix structural constituent, platelet-derived growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL4A1 itself. We selected most functions COL4A1 had, and list some proteins which have the same functions with COL4A1. You can find most of the proteins on our site.

Function Related Protein
extracellular matrix structural constituentCOL11A1A;TFPI2;COL27A1;ELN;COL3A1;IMPG2;PRELP;FBLN2;BGN
platelet-derived growth factor bindingPDGFRA;COL2A1;COL3A1;COL4A1;Pdgfa&Pdgfb;COL1A2;COL5A1;PDGFB;COL1A1

COL4A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL4A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL4A1.

Ywhae

Chen, SY; Lin, JS; et al. Modulation of tumor cell stiffness and migration by type IV collagen through direct activation of integrin signaling pathway. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 555:1-8(2014).
Ullah, M; Sittinger, M; et al. Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units. MATRIX BIOLOGY 32:452-465(2013).
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