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Official Full Name collagen, type IV, alpha 1
Synonyms COL4A1; collagen, type IV, alpha 1; collagen alpha-1(IV) chain; COL4A1 NC1 domain; collagen IV, alpha-1 polypeptide; collagen of basement membrane, alpha-1 chain; HANAC; POREN1; arresten
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Placenta
    • Tag :
    • His
    • S
    • His-SUMO
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human COL4A1-2713H Recombinant Human COL4A1 protein, His-SUMO-tagged E.coli His-SUMO
    Human COL4A1-001H Native Human COL4A1 Protein Placenta
    Human COL4A1-611H Recombinant Human COL4A1 protein, His & S-tagged E.coli His/S
    Mouse COL4A1-3735M Recombinant Mouse COL4A1 Protein Mammalian Cell His
    Chicken COL4A1-3967C Recombinant Chicken COL4A1 Mammalian Cell His

    COL4A1 involved in several pathways and played different roles in them. We selected most pathways COL4A1 participated on our site, such as PIK-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL4A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway PPP2R5B; ITGAV; ITGA9; PDGFRB; TSC1; PIK3R5; FGF1; CCNE2; VEGFB; FGF14
    Focal adhesion DOCK1; VCLA; AASS; COL1A1B; FYNB; TLN2A; TNK1; MYLK2; MYL9; TNN
    ECM-receptor interaction IBSP; LAMA2; ITGA11A; HSPG2; COL5A2A; ITGA4; COL6A5; SDC4; ITGB3; ITGB7
    Protein digestion and absorption SLC3A2; COL15A1; MME; SLC7A8; ATP1A3; ATP1B3; KCNN4; CPB2; SLC8A2; CELA2A
    Amoebiasis LAMB3; SERPINB2; ACTN1; IL6; PIK3R2; TNF; LAMC1; IFNG; LAMB2; COL4A6
    Pathways in cancer FGF20; FGFR1; PPARD; CDH1; Ar; TP53; FLT3LG; WNT11; FGF10; STAT5A
    Small cell lung cancer IKBKB; BIRC7; NFKB1; IKBKG; BCL2; PIK3R2; CCNE1; NOS2; AKT2; CCND1

    COL4A1 has several biochemical functions, for example, extracellular matrix structural constituent, platelet-derived growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL4A1 itself. We selected most functions COL4A1 had, and list some proteins which have the same functions with COL4A1. You can find most of the proteins on our site.

    Function Related Protein
    extracellular matrix structural constituent COL1A2; FBN1; TFPI2; LAMC1; COL27A1A; COL11A1B; COL8A2; COL1A1A; COL4A3; FBLN2
    platelet-derived growth factor binding PDGFRB; PDGFA; Pdgfa&Pdgfb; COL1A1; COL3A1; COL4A1; COL1A2; COL5A1; COL2A1; PDGFB

    COL4A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL4A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL4A1.


    Chen, SY; Lin, JS; et al. Modulation of tumor cell stiffness and migration by type IV collagen through direct activation of integrin signaling pathway. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 555:1-8(2014).
    Ullah, M; Sittinger, M; et al. Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units. MATRIX BIOLOGY 32:452-465(2013).

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