COL5A1
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Official Full Name
collagen, type V, alpha 1
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Others
- Bovine
- Chicken
- Human
- Rat
- Bovine
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | COL5A1-11437H | Recombinant Human COL5A1, His-tagged | E.coli | His | 243-591a.a. | |
Human | COL5A1-1656H | Recombinant Human COL5A1 Protein, GST-tagged | Wheat Germ | GST | ||
Human | COL5A1-2166HF | Recombinant Full Length Human COL5A1 Protein, GST-tagged | In Vitro Cell Free System | GST | 591 amino acids | |
Rat | COL5A1-1523R | Recombinant Rat COL5A1 Protein | Mammalian Cell | His | ||
Rat | COL5A1-1180R | Recombinant Rat COL5A1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | COL5A1-1180R-B | Recombinant Rat COL5A1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Bovine | Col-01B | Active Native Bovine Collagen Type V Protein | Bovine | N/A | ||
Chicken | COL5A1-6353C | Recombinant Chicken COL5A1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- COL5A1 Related Research Area
COL5A1 involved in several pathways and played different roles in them. We selected most pathways COL5A1 participated on our site, such as Amoebiasis, Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, which may be useful for your reference. Also, other proteins which involved in the same pathway with COL5A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Amoebiasis | HSPB1;Itgam&Itgb2;PIK3R2;CTSG;SERPINB9;COL4A5;GNA15;ADCY1;PIK3CD |
Assembly of collagen fibrils and other multimeric structures | COL6A3;BMP1;COL8A1;CTSS;MMP20;COL4A5;BMP1B;DST;LOXL1 |
Collagen biosynthesis and modifying enzymes | PPIB;COL17A1A;COL1A1;SERPINH1A;ADAMTS3;COL5A2;TLL2;COL5A1;LEPREL2 |
Collagen formation | COL6A3;PPIB;COL3A1;CRTAP;COL28A1A;CD151;COL8A2;COL1A2;ADAMTS2 |
ECM-receptor interaction | COL4A4;GP6;LAMA2;LAMB4;ITGA2B;COL1A1A;COL6A5;ITGB6;COL11A1A |
Extracellular matrix organization | BMP1A;COL2A1;LTBP2;DMP1;MATN3;COL1A1;CRTAP;LRP4;LOC100686744 |
Focal Adhesion | PAK2A;PDGFAB;COL6A3;LAMA5;MAPK10;AKT2;MYL9;CAPN2B;CAV3 |
COL5A1 has several biochemical functions, for example, extracellular matrix structural constituent, heparin binding, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by COL5A1 itself. We selected most functions COL5A1 had, and list some proteins which have the same functions with COL5A1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
extracellular matrix structural constituent | COL1A2;PXDN;COL11A2;COL24A1;MEPE;COL11A1B;LAMC1;IMPG1;MATN1 |
heparin binding | HSD17B12;FMODA;FGF12;AZU1;CLEC3B;REG4;SOST;MMP7;FGF14 |
integrin binding | COL5A1;LAMB2;GFAP;JAM3;FAP;FN1A;ADAMTS5;ESM1;FBLN1 |
metal ion binding | ROCK2B;BTR22;OTUD7A;SP8B;AMPD2;PLRDGB;DOM3Z;ROCK1;HDAC7A |
platelet-derived growth factor binding | COL3A1;PDGFB;COL4A1;COL1A2;PDGFRB;COL2A1;PDGFRA;COL5A1;COL1A1 |
proteoglycan binding | NID1;SLIT2;COL5A1;CTSB;CTSS;CTSK;CTSL1;CECR1;FCN2 |
COL5A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COL5A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COL5A1.
cona_canen; Tuba3a; PTPN1; CSNK2A2; TGM2; Actb; Ptpn2; Fbxw11; Ppp2r1a; Smad3
- Q&As
- Reviews
Q&As (5)
Ask a questionThe presence of normal COL5A1 protein is essential for maintaining the tensile strength and elasticity of tendons and ligaments.
The presence of COL5A1 protein in blood or tissue samples can be indicative of tendon damage, making it a potential biomarker for tendon injuries.
Some researchers are investigating the use of gene therapy or protein replacement therapy to address abnormalities in the production of COL5A1 protein in tendon injuries.
Mutations in the COL5A1 gene can lead to the production of abnormal type V collagen, resulting in the classical type of EDS characterized by joint hypermobility and skin hyperextensibility.
Yes, genetic testing can identify mutations in the COL5A1 gene, providing a means to diagnose conditions such as EDS and other connective tissue disorders.
Customer Reviews (3)
Write a reviewThe COL5A1 protein is renowned for its outstanding quality, making it an optimal choice to fulfill the requirements of my experimental investigations.
Its high purity and stability ensure reliable and reproducible results, which are paramount for achieving meaningful scientific outcomes.
With the COL5A1 protein's high-quality composition and reliability, researchers can confidently proceed with their studies, knowing that they have access to a protein that consistently delivers accurate results.
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