Recombinant Human COL5A1 Protein, GST-tagged

• Cat.No.: COL5A1-1656H
• Product Overview: Human COL5A1 full-length ORF ( AAH08760, 1 a.a. - 591 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. The encoded procollagen protein occurs commonly as the heterotrimer pro-alpha1(V)-pro-alpha1(V)-pro-alpha2(V). Mutations in this gene are associated with Ehlers-Danlos syndrome, types I and II. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 90.53 kDa
• AA Sequence: MGPPGPPGPRGPSGAPGADGPQGPP GGIGNPGAVGEKGEPGEAGEPGLPG EGGPPGPKGERGEKGESGPSGAAGP PGPKGPPGDDGPKGSPGPVGFPGDP GPPGEPGPAGQDGPPGDKGDDGEPG QTGSPGPTGEPGPSGPPGKRGPPGP AGPEGRQGEKGAKGEAGLEGPPGKT GPIGPQGAPGKPGPDGLRGIPGPVG EQGLPGSPGPDGPPGPMGPPGLPGL KGDSGPKGEKGHPGLIGLIGPPGEQ GEKGDRGLPGPQGSSGPKGEQGITG PSGPIGPPGPPGLPGPPGPKGAKGS SGPTGPKGEAGHPGPPGPPGPPGEV IQPLPIQASRTRRNIDASQLLDDGN GENYVDYADGMEEIFGSLNSLKLEI EQMKRPLGTQQNPARTCKDLQLCHP DFPDGEYWVDPNQGCSRDSFKVYCN FTAGGSTCVFPDKKSEGARITSWPK ENPGSWFSEFKRGKLLSYVDAEGNP VGVVQMTFLRLLSASAHQNVTYHCY QSVAWQDAATGSYDKALRFLGSNDE EMSYDNNPYIRALVDGCATKKGYQK TVLEIDTPKVEQVPIVDIMFNDFGE ASQKFGFEVGPACFMG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: COL5A1 collagen, type V, alpha 1 [ Homo sapiens ]
• Official Symbol: COL5A1
• Synonyms: COL5A1; collagen, type V, alpha 1; collagen alpha-1(V) chain; alpha 1 type V collagen
• Gene ID: 1289
• mRNA Refseq: NM_000093
• Protein Refseq: NP_000084
• MIM: 120215
• UniProt ID: P20908