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  • Official Full Name
  • coatomer protein complex subunit alpha
  • Background
  • In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by;non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent;subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP,;delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the;alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive;peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative;splicing results in multiple splice forms encoding distinct isoforms.
  • Synonyms
  • COPA; coatomer protein complex subunit alpha; Alpha coat protein; Alpha COP; Alpha COPI; AlphaCOP; Coatomer subunit alpha; COP A; COP I alpha; COPI alpha; FLJ26320; HEP COP; HEPCOP; Proxenin; Xenin; Xenopsin-related peptide
Cat.#:COPA-1691HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human COPA Protein, GST-tagged
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Cat.#:COPA-3056CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken COPA
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Cat.#:COPA-262ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish COPA
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Cat.#:COPA-0071BTag:His
Source (Host):E. coli or YeastSpecies:Bacillus subtilis
Product nameRecombinant Bacillus subtilis COPA protein, His-tagged
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Cat.#:copA-440BTag:N/A
Source (Host):E. coliSpecies:B.subtilis
Product nameRecombinant B.subtilis Copper Transporter ATPase, Domain A
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Cat.#:copA-442BTag:N/A
Source (Host):E. coliSpecies:B.subtilis
Product nameRecombinant B.subtilis Copper Transporter ATPase, Domain A+B
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Cat.#:copA-441BTag:N/A
Source (Host):E. coliSpecies:B.subtilis
Product nameRecombinant B.subtilis Copper Transporter ATPase, Domain B
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copA Related Articles

Preisig, O; Zufferey, R; et al. The Bradyrhizobium japonicum fixGHIS genes are required for the formation of the high-affinity cbb(3)-type cytochrome oxidase. ARCHIVES OF MICROBIOLOGY 165:297-305(1996).
ODERMATT, A; KRAPF, R; et al. INDUCTION OF THE PUTATIVE COPPER ATPASES, COPA AND COPB, OF ENTEROCOCCUS-HIRAE BY AG+ AND CU2+, AND AG+ EXTRUSION BY COPB. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 202:44-48(1994).
ODERMATT, A; SUTER, H; et al. PRIMARY STRUCTURE OF 2 P-TYPE ATPASES INVOLVED IN COPPER HOMEOSTASIS IN ENTEROCOCCUS-HIRAE. JOURNAL OF BIOLOGICAL CHEMISTRY 268:12775-12779(1993).