COX6A1

  • Official Full Name

    cytochrome c oxidase subunit VIa polypeptide 1

  • Overview

    Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.
  • Synonyms

    COX6A1; cytochrome c oxidase subunit VIa polypeptide 1; COX6A; cytochrome c oxidase subunit 6A1, mitochondrial; mitochondrial; COX VIa L; COX VIa-L; COX6AL; CX6A1_HUMAN; Cytochrome c oxidase polypeptide VIa liver; Cytochrome c oxidase polypeptide VIa-liver; Cytochrome c oxidase subunit 6A1; Cytochrome c oxidase subunit 6A1 mitochondrial; Cytochrome C oxidase subunit VIa homolog; Cytochrome c oxidase subunit VIA liver; Cytochrome c oxidase subunit VIA-liver; MGC104500; MS412;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human COX6A1-27583TH Recombinant Human COX6A1 Wheat Germ N/A 109 amino acids
Human COX6A1-1753H Recombinant Human COX6A1 Protein, GST-tagged Wheat Germ GST
Human COX6A1-7331HCL Recombinant Human COX6A1 293 Cell Lysate HEK293 N/A
Human COX6A1-91HF Recombinant Full Length Human COX6A1 Protein In Vitro Cell Free System 109 amino acids
Human COX6A1-5841H Recombinant Human COX6A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human COX6A1-2010HF Recombinant Full Length Human COX6A1 Protein, GST-tagged In Vitro Cell Free System GST 109 amino acids
Mouse COX6A1-3817M Recombinant Mouse COX6A1 Protein Mammalian Cell His
Mouse COX6A1-1915M Recombinant Mouse COX6A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse COX6A1-1915M-B Recombinant Mouse COX6A1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cox6a1-927M Recombinant Mouse Cox6a1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Zebrafish COX6A1-1433Z Recombinant Zebrafish COX6A1 Mammalian Cell His
Chicken COX6A1-4902C Recombinant Chicken COX6A1 Mammalian Cell His
Chicken COX6A1-4901C Recombinant Chicken COX6A1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

COX6A1 involved in several pathways and played different roles in them. We selected most pathways COX6A1 participated on our site, such as Alzheimers disease, Cardiac muscle contraction, Electron Transport Chain, which may be useful for your reference. Also, other proteins which involved in the same pathway with COX6A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Alzheimers diseasePSEN2;GSK3B;COX7C;COX4I2;ATP5H;GNAQ;COX8A;ATP5C1;LPL
Cardiac muscle contractionCOX7B;UQCR11;MYL2B;TPMA;COX7B2;COX5AA;CACNG6A;TNNT2;CACNA1DA
Electron Transport ChainCOX6B1;COX4I1;ATP5L;NDUFC2-KCTD14;COX8A;COX17;COX6A2;ATPIF1;COX6C
Gene ExpressionNFIX;NR4A2A;ZNF124;BRF1;ZNF157;SURF1;ZIK1;KRBOX4;ZNF114
Generic Transcription PathwayZNF484;NR2F6B;ZFP28;ZNF621;ZNF771;ZNF2;ZNF184;RNF111;RARAB
Huntingtons diseaseUQCRQ;NDUFB9;COX6A1;POLR2A;NDUFA12;SP1;NDUFC2;POLR2L;CREB3L2
Metabolic pathwaysZNF408;ybaS;B4GALT7;NT5C1B-RDH14;XYLB;SLC27A5;MCCC2;CERS1;ACOT2
MetabolismKCNB1;TM9SF1;CKMT2;HAS3;MED23;SLC46A1;FA2H;NUDT4B;COX10

COX6A1 has several biochemical functions, for example, cytochrome-c oxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by COX6A1 itself. We selected most functions COX6A1 had, and list some proteins which have the same functions with COX6A1. You can find most of the proteins on our site.

Function Related Protein
cytochrome-c oxidase activityCOX7A2L;SURF1;COX8C;COX5A;COX15;COX7C;CYB5A;COX7A2;COX7A1

COX6A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with COX6A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of COX6A1.

GRB2; HTT; CLPP

Research Area

Related articles

HUNTSMAN, MM; ISACKSON, PJ; et al. LAMINA-SPECIFIC EXPRESSION AND ACTIVITY-DEPENDENT REGULATION OF 7 GABA(A) RECEPTOR SUBUNIT MESSENGER-RNAS IN MONKEY VISUAL-CORTEX. JOURNAL OF NEUROSCIENCE 14:2236-2259(1994).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All COX6A1 Products

Required fields are marked with *

My Review for All COX6A1 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /
  • Service lnquiry:

Stay Updated on the Latest Bioscience Trends