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Official Full Name complexin 1
Background Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis.These proteins bind syntaxin, part of the SNAP receptor.The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release.
Synonyms CPLX1; complexin 1; complexin-1; CPX I; 921-S; Complexin I; CPLX1_HUMAN; CPX-I; CPX1; Synaphin 2; Synaphin-2
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CPLX1-3658H Recombinant Human CPLX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Cplx1-933M Recombinant Mouse Cplx1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human CPLX1-11519H Recombinant Human CPLX1, GST-tagged E.coli GST
    Human CPLX1-1785H Recombinant Human CPLX1 Protein, GST-tagged Wheat Germ GST
    Human CPLX1-27587TH Recombinant Human CPLX1, His-tagged E.coli His
    Human CPLX1-27588TH Recombinant Human CPLX1, His-tagged E.coli His
    Human CPLX1-305H Recombinant Human Complexin 1, His-tagged E.coli His
    Human CPLX1-627H Recombinant Human CPLX1 Protein, His-tagged E.coli His
    Human CPLX1-7313HCL Recombinant Human CPLX1 293 Cell Lysate HEK293 N/A
    Mouse CPLX1-3840M Recombinant Mouse CPLX1 Protein Mammalian Cell His
    Rat CPLX1-1566R Recombinant Rat CPLX1 Protein Mammalian Cell His
    Cynomolgus Monkey CPLX1-419C Recombinant Cynomolgus CPLX1 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque CPLX1-1003R Recombinant Rhesus monkey CPLX1 Protein, His-tagged Mammalian Cell His

    cplx1 involved in several pathways and played different roles in them. We selected most pathways cplx1 participated on our site, such as Acetylcholine Neurotransmitter Release Cycle, Dopamine Neurotransmitter Release Cycle, GABA synthesis, release, reuptake and degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with cplx1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Acetylcholine Neurotransmitter Release Cycle SYT1A; PPFIA4; BZRAP1; CHAT; PPFIA2; SLC18A3A; STXBP1A; UNC13B; CCDC167; PPFIA1
    Dopamine Neurotransmitter Release Cycle SYN1; PPFIA2; RERG; UNC13B; PPFIA4; CPLX1; CCDC167; SYN2; PPFIA1; LIN7A
    GABA synthesis, release, reuptake and degradation CPLX2L; RAB3AA; SNAP25A; CCDC167; SYT1A; SLC6A1A; STXBP1A; RAB3AB; SLC6A1B; SNAP25B
    Glutamate Neurotransmitter Release Cycle GLS2B; CPLX1; SNAP25A; ARL6IP5; ARL6IP5B; PPFIA1; SYT1A; SNAP25B; ARL6IP5A; STXBP1A
    Neuronal System KCND1; KCNH6A; KCNC4; SYN1; KCNH5A; KCNQ2; SLC1A7A; CPLX2L; KCNJ14; NSFB
    Neurotransmitter Release Cycle SYT1A; ARL6IP5; ARL6IP5A; Apba1; BZRAP1; RAB3AA; PPFIA2; SLC6A11; SLC6A1B; SLC1A2B
    Norepinephrine Neurotransmitter Release Cycle RAB3AB; PPFIA1; UNC13B; RERG; SNAP25A; SNAP25B; BZRAP1; CPLX1; PPFIA4; STXBP1A
    Serotonin Neurotransmitter Release Cycle SYN2; RERG; CPLX1; SYN1; SYN3; PPFIA1; PPFIA4; PPFIA2

    cplx1 has several biochemical functions, for example, neurotransmitter transporter activity, syntaxin-1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cplx1 itself. We selected most functions cplx1 had, and list some proteins which have the same functions with cplx1. You can find most of the proteins on our site.

    Function Related Protein
    neurotransmitter transporter activity GABRQ; CPLX1; SLC6A15; CPLX3
    syntaxin-1 binding DAPK1; STXBP1; GOLSYN; SNPH; VAMP2; CPLX1; SNAP25A; LRRK2; VAMP3; SLC6A4

    cplx1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cplx1 here. Most of them are supplied by our site. Hope this information will be useful for your research of cplx1.

    RXRB; pi3p; IQCB1

    Stenovec, M; Goncalves, PP; et al. Peptide Hormone Release Monitored From Single Vesicles in "Membrane Lawns" of Differentiated Male Pituitary Cells: SNAREs and Fusion Pore Widening. ENDOCRINOLOGY 154:1235-1246(2013).
    Keino, H; Watanabe, T; et al. Effect of Infliximab on Gene Expression Profiling in Behcet's Disease. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 52:7681-7686(2011).

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