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Official Full Name cystatin D
Background The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.
Synonyms CST5; cystatin D; cystatin-D; CST 5; Cystatin 5; CystatinD; Cysteine proteinase inhibitor; MGC71922; cystatin-5; cysteine-proteinase inhibitor
    • Species :
    • Human
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CST5-102H Recombinant Human CST5, His-tagged Insect Cell His
    Human CST5-1663H Recombinant Human CST5 protein, His & T7-tagged E.coli His/T7
    Human CST5-2028H Recombinant Human CST5 Protein, GST-tagged Wheat Germ GST
    Human CST5-3027HCL Recombinant Human CST5 cell lysate Human Cell N/A
    Human CST5-494H Recombinant Human CST5, His-tagged Mammalian cells His
    Human CST5-675H Recombinant Human CST5 protein, His-tagged HEK293 His

    CST5 involved in several pathways and played different roles in them. We selected most pathways CST5 participated on our site, such as Endochondral Ossification, Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with CST5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Endochondral Ossification SOX9A; PTHLHA; IFT88; ADAMTS1; NKX3.2; ADAMTS4; PTHLH; DDR2; PTH; SERPINH1
    Salivary secretion CALML5; MUC5B; Adcy4; PRKACG; PRH1; LYZ1; ATP1A3; AQP5; PRKG1; CST3

    CST5 has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CST5 itself. We selected most functions CST5 had, and list some proteins which have the same functions with CST5. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase inhibitor activity SERPINB13; CST4; NGP; SERPINB4; CST14B.1; WFDC2; AHSG2; CST7; BIRC5B; CST9L
    protein binding KCND3; PTK2; GFPT2; RASSF2; FAM71C; NRAP; PIFO; LOXL3; MAPK13; TFDP2

    CST5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CST5 here. Most of them are supplied by our site. Hope this information will be useful for your research of CST5.

    Gorodkiewicz, E; Sankiewicz, A; et al. Surface plasmon resonance imaging biosensors for aromatase based on a potent inhibitor and a specific antibody: Sensor development and application for biological material. CENTRAL EUROPEAN JOURNAL OF CHEMISTRY 12:557-567(2014).
    Ganeshnarayan, K; Velliyagounder, K; et al. Human salivary cystatin SA exhibits antimicrobial effect against Aggregatibacter actinomycetemcomitans. JOURNAL OF PERIODONTAL RESEARCH 47:661-673(2012).

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