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Official Full Name cathepsin G
Background Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Synonyms cathepsin G; CTSG; CG; CATG; MGC23078; OTTHUMP00000178752; CATG_HUMAN; Cathepsin G precursor; CTSG protein; EC; EC 3.4.21
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Neutrophil
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CTSG-1104H Recombinant Human CTSG protein, His & GST-tagged E.coli His/GST
    Human CTSG-1649H Native Human CTSG protein Human Neutrophil N/A
    Human CTSG-2106H Recombinant Human CTSG Protein, GST-tagged Wheat Germ GST
    Human CTSG-26490TH Native Human CTSG N/A
    Human CTSG-5327H Native Human Cathepsin G Human Neutrophil N/A
    Human CTSG-7193HCL Recombinant Human CTSG 293 Cell Lysate HEK293 N/A
    Human CTSG-8070H Native Human Neutrophil Cathepsin G Biotinylated Human Neutrophil N/A
    Human CTSG-855H Recombinant Human CTSG Protein, GST-His-tagged E.coli GST/His
    Mouse Ctsg-1105M Recombinant Mouse Ctsg protein, His & GST-tagged E.coli His/GST
    Mouse CTSG-4052M Recombinant Mouse CTSG Protein Mammalian Cell His
    Rat Ctsg-1106R Recombinant Rat Ctsg protein, His-tagged E.coli His
    Kit-0265 Cathepsin G Activity Assay Kit N/A
    Kit-2155 Cathepsin G Inhibitor Screening Kit N/A

    ctsg involved in several pathways and played different roles in them. We selected most pathways ctsg participated on our site, such as ACE Inhibitor Pathway, Activation of Matrix Metalloproteinases, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ctsg were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ACE Inhibitor Pathway AGTR2; CTSG; CMA1; ATP6AP2; CYP11B2; ACE; AGT; AGTR1
    Activation of Matrix Metalloproteinases TPSAB1; TIMP2A; CTSL2; CTSLL; MGC174152; FURINA; MMP17; TIMP2; MGC174155; MMP24
    Amoebiasis C8B; AASS; GNA15; PTK2; PLCB2; VCL; LAMA5; COL3A1; IL10; LAMA1
    Degradation of the extracellular matrix CTSD; TIMP2; ADAMTS18; NID1; CMA1; MMP12; CTSG; CTSS; MGC174857; MMP20
    Extracellular matrix organization CRTAP; COL5A1; CTSD; TIMP2A; COL9A1A; PCOLCE2B; DMP1; LTBP2; ADAM9; TIMP2B
    Lysosome AP1M1; ACP5B; AP1S2; PLA2G15; ACP5; AP3S1; ATP6V0B; SORT1A; GGA2; GALCB
    Metabolism of Angiotensinogen to Angiotensins CTSG; CPB1; CPB2; ACE; ATP6AP2; GZMH; CMA1; CPA3
    Metabolism of proteins RING1; ALG2; EIF4H; ASNA1; ADAMTSL1; TRAPPC1; TOMM20; ST6GALNAC1.2; GZMH; RAB27A

    ctsg has several biochemical functions, for example, heparin binding, peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ctsg itself. We selected most functions ctsg had, and list some proteins which have the same functions with ctsg. You can find most of the proteins on our site.

    Function Related Protein
    heparin binding CXCL11; FGF10; FGFBP1; F11; SFRP1; FSTL1; COL13A1; LPA; ZFP207; WISP3
    peptidase activity DESI2; TMPRSS4A; TMPRSS13B; ST14A; CAPN3A; MCPT2; PARLA; ADAMTS7; CTSL1B; HE1A
    protein binding ARL6IP5; PDE4C; TCTN2; HDGF2; SESN2; PIM2; BLNK; HIST1H2AM; TMSB4X; HOMER3
    serine-type endopeptidase activity APEH; KLK1B3; PRSS2; TMPRSS13A; PRSS52; TMPRSS11G; CTRC; KLK4; F7; GZMM

    ctsg has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ctsg here. Most of them are supplied by our site. Hope this information will be useful for your research of ctsg.

    KRT31; NOTCH2NL; dsdna_dcmdg:dcmdg; A2M; P/V/C

    Xu, C; Wang, JJ; et al. Adsorption of uranium by amidoximated chitosan-grafted polyacrylonitrile, using response surface methodology. CARBOHYDRATE POLYMERS 121:79-85(2015).
    Liu, GL; Li, DG; et al. Reconstruction of real tooth surfaces of spiral bevel pinions with modified offset. INVERSE PROBLEMS IN SCIENCE AND ENGINEERING 23:214-234(2015).

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