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CTSG

  • Official Full Name

    cathepsin G

  • Overview

    Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
  • Synonyms

    cathepsin G; CTSG; CG; CATG; MGC23078; OTTHUMP00000178752; CATG_HUMAN; Cathepsin G precursor; CTSG protein; EC 3.4.21.20; EC 3.4.21;

  • Native Proteins
  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Human Neutrophil
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • GST|His
  • His
  • His (Fc)
  • Avi
  • His|GST
  • SUMO
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CTSG-1649H Active Native Human CTSG protein Human Neutrophil N/A
Human CTSG-855H Recombinant Human CTSG Protein, GST-His-tagged E.coli GST/His
Human CTSG-2106H Recombinant Human CTSG Protein, GST-tagged Wheat Germ GST
Human CTSG-1104H Recombinant Human CTSG protein, His & GST-tagged E.coli His/GST Ile21~Leu255 (Accession # P08311)
Human CTSG-7193HCL Recombinant Human CTSG 293 Cell Lysate HEK293 N/A
Human CTSG-5327H Native Human Cathepsin G Human Neutrophil N/A
Human CTSG-26490TH Native Human CTSG N/A
Human CTSG-2349HF Recombinant Full Length Human CTSG Protein, GST-tagged In Vitro Cell Free System GST 255 amino acids
Human CTSG-8070H Native Human Neutrophil Cathepsin G Biotinylated Human Neutrophil N/A
Human CTSG-1886H Recombinant Human CTSG Protein (Ile21-Leu255), N-GST tagged E.coli N-GST Ile21-Leu255
Mouse CTSG-4052M Recombinant Mouse CTSG Protein Mammalian Cell His
Mouse Ctsg-1105M Recombinant Mouse Ctsg protein, His & GST-tagged E.coli His/GST Ile21~Thr261 (Accession # P28293)
Mouse Ctsg-2759M Recombinant Mouse Ctsg protein, His-SUMO-tagged E.coli His-SUMO 21-261aa
Mouse CTSG-2067M Recombinant Mouse CTSG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse CTSG-2067M-B Recombinant Mouse CTSG Protein Pre-coupled Magnetic Beads HEK293
Rat Ctsg-1106R Recombinant Rat Ctsg protein, His-tagged E.coli His Gly51~Tyr250 (Accession # G3V9Q7)
Kit-0265 Cathepsin G Activity Assay Kit N/A
Kit-2155 Cathepsin G Inhibitor Screening Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CTSG Related Articles

CTSG involved in several pathways and played different roles in them. We selected most pathways CTSG participated on our site, such as ACE Inhibitor Pathway, Activation of Matrix Metalloproteinases, Amoebiasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTSG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ACE Inhibitor PathwayACE;ATP6AP2;AGTR1;AGT;AGTR2;CYP11B2;CMA1;CTSG
Activation of Matrix MetalloproteinasesMMP17;CTSG;CMA1;FURINB;TPSAB1;MGC174155;MMP15;MGC174152;TIMP2A
AmoebiasisSERPINB10;PRKCA;LAMA1;IL1B2;TGFB1;ARG1;RAB7B;GNAQ;TNF
Degradation of the extracellular matrixMMP24;CTSD;ADAMTS18;COL25A1;ADAMTS5;ADAMTS4;MMP15;MMP19;CTS7
Extracellular matrix organizationADAMTS3;ADAMTS18;COL10A1A;LOC100514666;ADAMTS2;ADAMTS4;DDR1;COL8A1A;MMP12
LysosomeAP3D1;GAA;IGF2R;ACP2;ATP6V0A2;ACP5B;AP3M1;NPC2;CTSK
Metabolism of Angiotensinogen to AngiotensinsATP6AP2;CPB2;GZMH;CMA1;CPB1;ACE;CTSG;CPA3
Metabolism of proteinsB3GNT3;ARSH;YIF1A;MAN1A2;THSD1;EEF1D;CBX4;SEC61B;CBX8

CTSG has several biochemical functions, for example, heparin binding, peptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTSG itself. We selected most functions CTSG had, and list some proteins which have the same functions with CTSG. You can find most of the proteins on our site.

Function Related Protein
heparin bindingCYR61L1;CCDC80;NRP1;NOV;CFH;LIPI;FGF14;THBS2;FGF4
peptidase activityTPP1;BAP1;CELA3B;CTSSB.2;PM20D1.1;ZMPSTE24;ADAM25;KLK5;CAPN3B
protein bindingETV7;NR0B2;JUND;PPP1R12C;NECAB3;MAGOHB;PSMA6;MYOM1;DNAJB6
serine-type endopeptidase activityELA2L;HPR;PREP;F2;HABP2;PRSS44;MMP2;F12;F7I

CTSG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTSG here. Most of them are supplied by our site. Hope this information will be useful for your research of CTSG.

KRT31; NOTCH2NL; dsdna_dcmdg:dcmdg; A2M; P/V/C

Xu, C; Wang, JJ; et al. Adsorption of uranium by amidoximated chitosan-grafted polyacrylonitrile, using response surface methodology. CARBOHYDRATE POLYMERS 121:79-85(2015).
Liu, GL; Li, DG; et al. Reconstruction of real tooth surfaces of spiral bevel pinions with modified offset. INVERSE PROBLEMS IN SCIENCE AND ENGINEERING 23:214-234(2015).
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