|Official Full Name||cytochrome P450, family 2, subfamily A, polypeptide 13|
|Background||This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.|
|Synonyms||CYP2A13; cytochrome P450, family 2, subfamily A, polypeptide 13; cytochrome P450, subfamily IIA (phenobarbital inducible), polypeptide 13; cytochrome P450 2A13; CPAD; CYP2A; CYPIIA13; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
cyp2a13 involved in several pathways and played different roles in them. We selected most pathways cyp2a13 participated on our site, such as Aflatoxin B1 metabolism, Aflatoxin activation and detoxification, Biological oxidations, which may be useful for your reference. Also, other proteins which involved in the same pathway with cyp2a13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Aflatoxin B1 metabolism||CYP1A2; FAM84B; CYP3A4; CYP2A13; PRKRA|
|Aflatoxin activation and detoxification||DPEP2; ACY3; GGTLC1; ACY3.1; CYP2A13; CYP3C4; CYP1A2; CYP2Y3; CYP3A4; ACY3.2|
|Biological oxidations||CYP2J2; SULT4A1; UGT1B5; CYP2D6; GLYAT; CYP21A2; ADH1A; NAT2; CYP11A1; ADH6|
|CYP2E1 reactions||CYP2C8; CYP2C19; CYP2A7; CYP2D6; CYP2C9; CYP2S1; CYP2A6; CYP2E1; CYP2F1; CYP2B6|
|Chemical carcinogenesis||ADH2-2; CYP3A5; ADH2-1; CYP1A1; ADH5; CCBL2; ALDH3B2; CBR1; PTGS2; UGT2B7|
|Cytochrome P450 - arranged by substrate type||CYP3A7-CYP3AP1; CYP51A1; CYP17A1; CYP1A1; CYP2C8; CYP24A1; CYP2N13; CYP2K6; CYP3A5; CYP7A1|
|Fatty acids||CYP2N13; CYP4A11; CYP2A7; CYP2D6; CYP2J2; CYP2F1; CYP4F11; CYP2V1; CYP2B6; CYP4B1|
|Metabolism||AKR1C21; NDUFAF5; NUDT10; HAS3; GSTO2; DAO1; PCBD1; CYP2K6; CYP2W1; SGMS2|
cyp2a13 has several biochemical functions, for example, arachidonic acid epoxygenase activity, aromatase activity, heme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by cyp2a13 itself. We selected most functions cyp2a13 had, and list some proteins which have the same functions with cyp2a13. You can find most of the proteins on our site.
|arachidonic acid epoxygenase activity||CYP2A7; CYP4A11; CYP2P7; CYP2D10; CYP2P9; CYP4F18; CYP2C19; CYP2J6; CYP2S1; CYP2F1|
|aromatase activity||CYP2U1; CYP3A25; CYP2C38; CYP2C37; CYP2A13; CYP2J6; CYP4B1; CYP1A1; CYP2C55; CYP2D10|
|heme binding||CYP4V2; SRC; CYP2F1; TDO2A; CYP27B1; CYB5D2; CYP8B1; CYP3A5; NOX5; CYP17A2|
|iron ion binding||ALOX5A; ISCUB; CYP7B1; HBB-B2; FDX1; CYP4B1; CYP2K17; CYP2B6; CYP2B19; EGLN1|
|oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen||CYP2A6; CYP2A12; CYP2AA12; CYP3C1; CYP2U1; CYP2C38; CYP2P9; CYP2AD6; CYP1A2; CYP2D9|
|oxygen binding||HBM; HBBE2; CYP2J2; CYP2AD6; CYP2B19; CYP2P7; HBQ1; NGB; HBAA; CYP3A7|
|steroid hydroxylase activity||CYP2C54; CYP2D9; CYP2C39; CYP2C8; CYP2AD3; BRSK2; CYP1A1; CYP2C38; CYP2K19; CYP2X7|
cyp2a13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with cyp2a13 here. Most of them are supplied by our site. Hope this information will be useful for your research of cyp2a13.