Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Human DDX41 Protein, GST-tagged

Cat.No. : DDX41-2488H
Product Overview : Human DDX41 full-length ORF ( NP_057306.2, 1 a.a. - 622 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD box protein family and interacts with several spliceosomal proteins. In addition, the encoded protein may recognize the bacterial second messengers cyclic di-GMP and cyclic di-AMP, resulting in the induction of genes involved in the innate immune response. [provided by RefSeq, Jan 2017]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 96.2 kDa
AA Sequence : MEESEPERKRARTDEVPAGGSRSEA EDEDDEDYVPYVPLRQRRQLLLQKL LQRRRKGAAEEEQQDSGSEPRGDED DIPLGPQSNVSLLDQHQHLKEKAEA RKESAKEKQLKEEEKILESVAEGRA LMSVKEMAKGITYDDPIKTSWTPPR YVLSMSEERHERVRKKYHILVEGDG IPPPIKSFKEMKFPAAILRGLKKKG IHHPTPIQIQGIPTILSGRDMIGIA FTGSGKTLVFTLPVIMFCLEQEKRL PFSKREGPYGLIICPSRELARQTHG ILEYYCRLLQEDSSPLLRCALCIGG MSVKEQMETIRHGVHMMVATPGRLM DLLQKKMVSLDICRYLALDEADRMI DMGFEGDIRTIFSYFKGQRQTLLFS ATMPKKIQNFAKSALVKPVTINVGR AGAASLDVIQEVEYVKEEAKMVYLL ECLQKTPPPVLIFAEKKADVDAIHE YLLLKGVEAVAIHGGKDQEERTKAI EAFREGKKDVLVATDVASKGLDFPA IQHVINYDMPEEIENYVHRIGRTGR SGNTGIATTFINKACDESVLMDLKA LLLEAKQKVPPVLQVLHCGDESMLD IGGERGCAFCGGLGHRITDCPKLEA MQTKQVSNIGRKDYLAHSSMDF
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 [ Homo sapiens ]
Official Symbol : DDX41
Synonyms : DDX41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; probable ATP-dependent RNA helicase DDX41; ABS; MGC8828; 2900024F02Rik; DEAD box protein 41; putative RNA helicase; DEAD-box protein abstrakt; DEAD box protein abstrakt homolog;
Gene ID : 51428
mRNA Refseq : NM_016222
Protein Refseq : NP_057306
MIM : 608170
UniProt ID : Q9UJV9

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
In which cellular compartments is DDX41 predominantly localized? 12/07/2022

DDX41 is predominantly localized in the cytoplasm of cells, where it carries out its functions in nucleic acid recognition and immune sensing.

What is the primary function of DExD/H-box helicase 41 (DDX41) in cellular processes and nucleic acid metabolism? 06/06/2022

DExD/H-box helicase 41 (DDX41) functions in cellular processes, primarily playing a role in nucleic acid metabolism and immune responses.

How does DDX41 recognize and interact with nucleic acids, including RNA and DNA? 04/17/2022

DDX41 recognizes and interacts with nucleic acids, including RNA and DNA, through its DExD/H-box helicase domain.

What is the role of DDX41 in innate immune responses, particularly in sensing viral or microbial infections? 02/06/2021

The role of DDX41 in innate immune responses involves sensing viral or microbial infections and triggering antiviral signaling pathways.

What diseases or conditions are associated with dysregulation or abnormal expression of DDX41? 05/06/2020

Dysregulation or abnormal expression of DDX41 is associated with conditions such as myelodysplastic syndromes and certain cancers.

How does DDX41 contribute to the activation of antiviral signaling pathways, such as the interferon response? 07/26/2018

DDX41 contributes to the activation of antiviral signaling pathways, including the induction of interferon responses against viral infections.

Are there therapeutic implications or potential targets related to DDX41 in diseases involving immune responses? 06/16/2017

There are potential therapeutic implications related to DDX41 in diseases involving immune responses, making it a target for drug development.

Customer Reviews (3)

Write a review
Reviews
04/16/2020

    Compatibility with standard laboratory instruments made the product user-friendly in our well-equipped facility.

    11/11/2019

      Our suggestions for enhancements were acknowledged, fostering a collaborative relationship with the product's provider.

      01/12/2019

        Clear and comprehensive training materials provided a solid foundation for understanding the product's application.

        Ask a Question for All DDX41 Products

        Required fields are marked with *

        My Review for All DDX41 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends