DNAJA2
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Official Full Name
DnaJ (Hsp40) homolog, subfamily A, member 2
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Overview
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. -
Synonyms
DNAJA2; DnaJ (Hsp40) homolog, subfamily A, member 2; dnaJ homolog subfamily A member 2; CPR3; DNAJ; DNJ3; HIRIP4; Cell cycle progression 3 protein; Cell cycle progression restoration gene 3 protein; CPR 3; Dj3; DJA 2; DJA2; DnaJ (Hsp40) homolog subfamily A member 2; DNAJA 2; DNJ 3; DNJA2_HUMAN; HIRA interacting protein 4; HIRA-interacting protein 4; HIRIP 4; OTTHUMP00000164136; PRO3015; RDJ 2; RDJ2; Renal carcinoma antigen NY REN 14; Renal carcinoma antigen NY-REN-14;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
DNAJA2 involved in several pathways and played different roles in them. We selected most pathways DNAJA2 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | CALR3B;BAG2;DNAJC5B;MAPK8;UBE2D2;DNAJA2;CAPN2A;PARK2;SSR4 |
DNAJA2 has several biochemical functions, for example, ATP binding, chaperone binding, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJA2 itself. We selected most functions DNAJA2 had, and list some proteins which have the same functions with DNAJA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | BRAF;SGK196;TSSK5;DDX18;CDC42BPA;CDK14;PHKG2;DDX31;TPK1 |
| chaperone binding | TG;TBCD;HES1;PFDN4;AHSA2;DNAJB4;DNAJC10;HYOU1;HSPE1 |
| glycoprotein binding | ERLEC1;BMPR1B;FBXO6;FLNA;CANX;FOXRED2;LACRT;LGALS1;ITGAM |
| heat shock protein binding | HSPA1A;DNAJA3B;PARK2;CDC37L1;PACRG;DLST;APAF1;HDAC2;LIMK1 |
| metal ion binding | RUNX1T1;CNOT4B;LOXL2A;AOX3L1;PRDM12;ETFDH;ZNF395;ZNF518A;EME1 |
| protein binding | HOXB9;CTSZ;IRF8;SFRP1;EDC3;RPGR;NPHS1;RAB39B;TRADD |
| unfolded protein binding | DNAJA3A;NDUFAF1;SRSF12;TAPBP;RUVBL2;CALR3B;SCG5;MKKS;CDC37 |
DNAJA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJA2.
AICDA; EGFR; P; DNAJA4; NUDC; Tubb4b; SMAD3; Tubb5; SMAD2; TOE1; 15-deoxy-delta(12,14; IRS4; PTBP3
- Q&As
- Reviews
Q&As (5)
Ask a questionDNAJA2 can act as a synergistic molecular chaperone to help cellular protein translation, folding, degradation, etc.
Overexpression of DNAJA2 promotes JEV proliferation.
They both belong to the DnaJ family of A-type proteins and they can interact with each other.
DNAJA2 interacts with NS3.
Inhibition of DNAJA2 expression promotes ubiquitination modification of NS3 and NS5.
Customer Reviews (3)
Write a reviewCheap price, high quality products, worth buying again.
The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.
I have a dedicated staff member who is in contact with me and he keep me informed of the progress of my experiments.
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