DNAJA3
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Official Full Name
DnaJ (Hsp40) homolog, subfamily A, member 3 -
Overview
Tid1, also known as human Tid56 and DnaJ (Hsp40)homolog, subfamily A member 3 (DNAJA3), a member of the DnaJ family of cochaperones1,2. DnaJ proteins function as regulatory factors for the heat shock protein 70 (Hsp70) family, and are characterized by a h -
Synonyms
DNAJA3;DnaJ (Hsp40) homolog, subfamily A, member 3;TID1;dnaJ homolog subfamily A member 3, mitochondrial;hTid 1;dnaJ protein Tid-1;tumorous imaginal discs protein Tid56 homolog;hepatocellular carcinoma-associated antigen 57;HCA57;hTID-1;FLJ45758
Recombinant Proteins
- Human
- Mouse
- Wheat Germ
- HEK293
- Mammalian Cells
- In Vitro Cell Free System
- GST
- Non
- Flag
- DDK
- Myc
- Avi
- Fc
- His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| DNAJA3-2727H | Recombinant Human DNAJA3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| DNAJA3-6893HCL | Recombinant Human DNAJA3 293 Cell Lysate | HEK293 | Human | Non |
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| DNAJA3-1700HFL | Recombinant Full Length Human DNAJA3 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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| Dnaja3-2593M | Recombinant Mouse Dnaja3 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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| DNAJA3-3957HF | Recombinant Full Length Human DNAJA3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 480 amino acids |
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| DNAJA3-773H | Recombinant Human DNAJA3 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| DNAJA3-773H-B | Recombinant Human DNAJA3 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| DNAJA3-860H | Recombinant Human DNAJA3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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Involved Pathway
DNAJA3 involved in several pathways and played different roles in them. We selected most pathways DNAJA3 participated on our site, such as Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNAJA3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Viral carcinogenesis | HIST1H2BH,CDK1,NFKB1,GTF2A1L,GTF2H3,GTF2H4,HDAC7,ACTN2,ATP6V0D2,SP100 |
Protein Function
DNAJA3 has several biochemical functions, for example, ATP binding,GTPase regulator activity,NF-kappaB binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DNAJA3 itself. We selected most functions DNAJA3 had, and list some proteins which have the same functions with DNAJA3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor tyrosine kinase binding | ZNF259,SOCS5,PTPN2,HYAL2,TRP53,PTPN1,GAS6,MYOC,TP53,PCNA |
| GTPase regulator activity | RALGDS,RGS12,RGS12B,PCP2,GPSM1B,TSC1,TSC1A,ARL2BP,GPSM2,RGS14A |
| NF-kappaB binding | RNF25,RELA,AP1S2,NPM1,HIF1AN,GSK3B,PSMA6,HDAC2,TAF4B,BCL10 |
| heat shock protein binding | NFKB1,PDXP,GRXCR2,HSPA8,DNAJC7,HSPA1L,PPID,DNAJA3B,TFAM,CDC37L1 |
| metal ion binding | RXRAA,ROCK2A,HMGCLL1,MMP14B,PPP1R10,ZNF292B,KLF10,NR5A5,ZNF174,COL1A1 |
| protein kinase binding | ILK,PRC1,PPP1CB,DNM1,RAB11FIP2,CDKN2A,DBF4B,CYLD,LAT,GATA4 |
| protein binding | ITGA3,NUCB2,ARNT,TOP3A,L3MBTL1,CBX8,OLFM4,ARID5A,IL18R1,S1PR2 |
| ATP binding | PFKFB2,PDGFRA,STRADA,ABCC11,HSPA13,PPP1CA,MAPK14B,ATP7B,PAN3,NEK1 |
| unfolded protein binding | LRPAP1,ERLEC1,CHAF1B,CRYABB,DNAJB6,RP2,CCT5,HSPA1L,CHAF1A,CALR3B |
Interacting Protein
DNAJA3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNAJA3 here. Most of them are supplied by our site. Hope this information will be useful for your research of DNAJA3.
KDM1A;Stat5b;CARM1;PRMT6;MET;TNFRSF1A;TNFRSF1B;STAT1;Stat1;STAT5B;NFKB2;RELA;MAP3K1
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References
- Mulaw, MA; Krause, AJ; et al. CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12. LEUKEMIA 26:1012-1019(2012).
