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Official Full Name destrin (actin depolymerizing factor)
Background The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
Synonyms DSTN; destrin (actin depolymerizing factor); destrin; ACTDP; ADF; 2610043P17Rik; Actin depolymerizing factor; Actin-depolymerizing factor; AU042046; bA462D18.2; corn1; DEST_HUMAN; DSN; Sid 23; sid23p; bA462D18.2 (destrin (actin depolymerizing factor ADF) (ACTDP))
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human DSTN-30180H Recombinant Human DSTN protein, GST-tagged E.coli GST
    Human DSTN-1638H Recombinant Human DSTN protein, His & GST-tagged E.coli His/GST
    Human DSTN-26582TH Recombinant Human DSTN, His-tagged E.coli His
    Human DSTN-2894H Recombinant Human DSTN Protein, GST-tagged Wheat Germ GST
    Human DSTN-6805HCL Recombinant Human DSTN 293 Cell Lysate HEK293 N/A
    Human DSTN-6844H Recombinant Human Destrin (actin depolymerizing factor), His-tagged E.coli His
    Mouse Dstn-2665M Recombinant Mouse Dstn Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat DSTN-1963R Recombinant Rat DSTN Protein Mammalian Cell His
    Rhesus Macaque DSTN-1337R Recombinant Rhesus monkey DSTN Protein, His-tagged Mammalian Cell His
    Chicken DSTN-7076C Recombinant Chicken DSTN Mammalian Cell His

    DSTN involved in several pathways and played different roles in them. We selected most pathways DSTN participated on our site, such as Androgen receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with DSTN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Androgen receptor signaling pathway CDKN1A; NCOA2; KAT7; KAT5; CREBBP; HTATIP; RNF14; PIAS3; RUNX2A; HMGB2A

    DSTN has several biochemical functions, for example, actin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by DSTN itself. We selected most functions DSTN had, and list some proteins which have the same functions with DSTN. You can find most of the proteins on our site.

    Function Related Protein
    actin binding KLHL2; CAPGA; CYFIP1; MYH1; KLHL3; GMFB; PTK2; SHROOM4; MTAP1B; GC
    protein binding CCNF; AGO3; PIAS4; MAPKAPK3; ZNF143; RAD51; MATN2; PTCH1; S100P; ITGA1

    DSTN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DSTN here. Most of them are supplied by our site. Hope this information will be useful for your research of DSTN.

    ACTG1; ACTB; PS1TP5BP1; CFL2; TAX1BP1; 1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate

    Nakano, S; Kanamori, T; et al. Detection and characterization of a rat parotid gland protein kinase that catalyzes phosphorylation of matured destrin at Ser-2. ARCHIVES OF ORAL BIOLOGY 48:649-661(2003).
    Howes, EA; Hurst, SM; et al. Actin and actin-binding proteins in bovine spermatozoa: Potential role in membrane remodeling and intracellular signaling during epididymal maturation and the acrosome reaction. JOURNAL OF ANDROLOGY 22:62-72(2001).

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