Recombinant Human DUSP18 Protein, GST-tagged DUSP18-2931H

Recombinant Human DUSP18 Protein, GST-tagged

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Recombinant Human DUSP18 Protein, GST-tagged

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Cat.No. : DUSP18-2931H
Product Overview : Human DUSP18 full-length ORF ( NP_689724.3, 1 a.a. - 188 a.a.) recombinant protein with GST-tag at N-terminal.
Description : Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP18 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 47.5 kDa
AA Sequence : MTAPSCAFPVQFRQP SVSGLSQITKSLYIS NGVAANNKLMLSSNQ ITMVINVSVEVVNTL YEDIQYMQVPVADSP NSRLCDFFDPIADHI HSVEMKQGRTLLHCA AGVSRSAALCLAYLM KYHAMSLLDAHTWTK SCRPIIRPNSGFWEQ LIHYEFQLFGKNTVH MVSSPVGMIPDIYEK EVRLMIPL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : DUSP18 dual specificity phosphatase 18 [ Homo sapiens ]
Official Symbol : DUSP18
Synonyms : DUSP18; dual specificity phosphatase 18; dual specificity protein phosphatase 18; DUSP20; LMW-DSP20; low molecular weight dual specificity phosphatase 20; DSP18; LMWDSP20; bK963H5.1; MGC32658;
Gene ID : 150290
mRNA Refseq : NM_152511
Protein Refseq : NP_689724
MIM : 611446
UniProt ID : Q8NEJ0

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