Recombinant Human EIF2A Protein, GST-tagged

• Cat.No.: EIF2A-3145H
• Product Overview: Human EIF2A full-length ORF ( AAH11885.1, 1 a.a. - 585 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly(U)-directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 91.4 kDa
• AA Sequence: MAPSTPLLTVRGSEGLYMVNGPPHF TESTVFPRESGKNCKVCIFSKDGTL FAWGNGEKVNIISVTNKGLLHSFDL LKAVCLEFSPKNTVLATWQPYTTSK DGTAGIPNLQLYDVKTGTCLKSFIQ KKMQNWCPSWSEDETLCARNVNNEV HFFENNNFNTIANKLHLQKINDFVL SPGPQPYKVAVYVPGSKGAPSFVRL YQYPNFAGPHAALANKSFFKADKVT MLWNKKATAVLVIASTDVDKTGASY YGEQTLHYIATNGESAVVQLPKNGP IYDVVWNSSSTEFCAVYGFMPAKAT IFNLKCDPVFDFGTGPRNAAYYSPH GHILVLAGFGNLRGQMEVWDVKNYK LISKPVASDSTYFAWCPDGEHILTA TCAPRLRVNNGYKIWHYTGSILHKY DVPSNAELWQVSWQPFLDGIFPAKT ITYQAVPSEVPNEEPKVATAYRPPA LRNKPITNSKLHEEEPPQNMKPQSG NDKPLSKTALKNQRKHEAKKAAKQE ARSDKSPDLAPTPAPQSTPRNTVSQ SISGDPEIDKKIKNLKKKLKAIEQL KEQAATGKQLEKNQLEKIQKETALL QELEDLKLGI
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EIF2A eukaryotic translation initiation factor 2A, 65kDa [ Homo sapiens ]
• Official Symbol: EIF2A
• Synonyms: EIF2A; eukaryotic translation initiation factor 2A, 65kDa; eukaryotic translation initiation factor 2A; EIF 2A; 65 kDa eukaryotic translation initiation factor 2A; CDA02; EIF-2A; MST089; MSTP004; MSTP089
• Gene ID: 83939
• mRNA Refseq: NM_032025
• Protein Refseq: NP_114414
• MIM: 609234
• UniProt ID: Q9BY44