|Official Full Name||eukaryotic translation termination factor 1|
|Background||This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]|
|Synonyms||ETF1; eukaryotic translation termination factor 1; ERF; RF1; ERF1; TB3-1; D5S1995; SUP45L1; eukaryotic peptide chain release factor subunit 1; protein Cl1; polypeptide chain release factor 1; sup45 (yeast omnipotent suppressor 45) homolog-like 1;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
etf1 involved in several pathways and played different roles in them. We selected most pathways etf1 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with etf1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|mRNA surveillance pathway||PABPC1L2A; RNMT; PPP2R5D; SSU72; PNN; SMG5; NXT2; NCBP1; CPSF2; PPP2R5CB|
etf1 has several biochemical functions, for example, RNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by etf1 itself. We selected most functions etf1 had, and list some proteins which have the same functions with etf1. You can find most of the proteins on our site.
|RNA binding||HNRNPU; SRP9; PABPC5; ZFP385C; RPL39L; C14orf166; RPL6; TEP1; TNRC6B; HDLBPA|
|poly(A) RNA binding||FKBP3; RPS27.1; SR140; BCLAF1; CLNS1A; CCDC86; TSFM; ZC3H14; SNRPD3; NXF3|
|protein binding||NCAPH2; LSM3; STX1A; UBE3A; SNRPB2; TMEM106C; C6orf108; SLC25A4; KIF5C; CPNE3|
|ribosome binding||CPEB4; EIF2S1A; EIF2A; SEC61B; MTOR; CPEB3; RICTOR; EIF3K; CPEB1B; ERI1|
|translation release factor activity||GSPT2; MTRF1; ETF1; GSPT1L|
|translation release factor activity, codon specific||ETF1; MTRF1; ETF1B; MTRF1L; ETF1A|
|translation termination factor activity||ETF1|
etf1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with etf1 here. Most of them are supplied by our site. Hope this information will be useful for your research of etf1.
KEAP1; GSPT1; a8k1f4_human; MLF1; PSMD2; IKBKE; TRMT10C; GSPT2; FKBPL; TRAF6; Mphosph9; FGFR1OP; ALB; VCAM1