etf1 Protein, eukaryotic translation termination factor 1


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Official Full Name eukaryotic translation termination factor 1
Background This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]
Synonyms ETF1; eukaryotic translation termination factor 1; ERF; RF1; ERF1; TB3-1; D5S1995; SUP45L1; eukaryotic peptide chain release factor subunit 1; protein Cl1; polypeptide chain release factor 1; sup45 (yeast omnipotent suppressor 45) homolog-like 1;
    • Species :
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ETF1-12564H Recombinant Human ETF1, GST-tagged E.coli GST
    Human ETF1-1397H Recombinant Human ETF1 protein, His & T7-tagged E.coli His/T7
    Human ETF1-28695TH Recombinant Human ETF1 Wheat Germ N/A
    Human ETF1-3514H Recombinant Human ETF1 Protein, GST-tagged Wheat Germ GST
    Human ETF1-5893H Recombinant Human ETF1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ETF1-6533HCL Recombinant Human ETF1 293 Cell Lysate HEK293 N/A
    Rat ETF1-2158R Recombinant Rat ETF1 Protein Mammalian Cell His
    Rhesus Macaque ETF1-1508R Recombinant Rhesus monkey ETF1 Protein, His-tagged Mammalian Cell His

    etf1 involved in several pathways and played different roles in them. We selected most pathways etf1 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with etf1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mRNA surveillance pathway PABPC1L2A; RNMT; PPP2R5D; SSU72; PNN; SMG5; NXT2; NCBP1; CPSF2; PPP2R5CB

    etf1 has several biochemical functions, for example, RNA binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by etf1 itself. We selected most functions etf1 had, and list some proteins which have the same functions with etf1. You can find most of the proteins on our site.

    Function Related Protein
    RNA binding HNRNPU; SRP9; PABPC5; ZFP385C; RPL39L; C14orf166; RPL6; TEP1; TNRC6B; HDLBPA
    poly(A) RNA binding FKBP3; RPS27.1; SR140; BCLAF1; CLNS1A; CCDC86; TSFM; ZC3H14; SNRPD3; NXF3
    protein binding NCAPH2; LSM3; STX1A; UBE3A; SNRPB2; TMEM106C; C6orf108; SLC25A4; KIF5C; CPNE3
    ribosome binding CPEB4; EIF2S1A; EIF2A; SEC61B; MTOR; CPEB3; RICTOR; EIF3K; CPEB1B; ERI1
    translation release factor activity GSPT2; MTRF1; ETF1; GSPT1L
    translation release factor activity, codon specific ETF1; MTRF1; ETF1B; MTRF1L; ETF1A
    translation termination factor activity ETF1

    etf1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with etf1 here. Most of them are supplied by our site. Hope this information will be useful for your research of etf1.

    KEAP1; GSPT1; a8k1f4_human; MLF1; PSMD2; IKBKE; TRMT10C; GSPT2; FKBPL; TRAF6; Mphosph9; FGFR1OP; ALB; VCAM1

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