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Recombinant Human ETF1 Protein, GST-tagged

Cat.No. : ETF1-3514H
Product Overview : Human ETF1 full-length ORF ( NP_004721.1, 1 a.a. - 437 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
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Description : This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X. [provided by RefSeq, Aug 2013]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 75.4 kDa
AA Sequence : MADDPSAADRNVEIWKIKKLIKSLE AARGNGTSMISLIIPPKDQISRVAK MLADEFGTASNIKSRVNRLSVLGAI TSVQQRLKLYNKVPPNGLVVYCGTI VTEEGKEKKVNIDFEPFKPINTSLY LCDNKFHTEALTALLSDDSKFGFIV IDGSGALFGTLQGNTREVLHKFTVD LPKKHGRGGQSALRFARLRMEKRHN YVRKVAETAVQLFISGDKVNVAGLV LAGSADFKTELSQSDMFDQRLQSKV LKLVDISYGGENGFNQAIELSTEVL SNVKFIQEKKLIGRYFDEISQDTGK YCFGVEDTLKALEMGAVEILIVYEN LDIMRYVLHCQGTEEEKILYLTPEQ EKDKSHFTDKETGQEHELIESMPLL EWFANNYKKFGATLEIVTDKSQEGS QFVKGFGGIGGILRYRVDFQGMEYQ GGDDEFFDLDDY
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ETF1 eukaryotic translation termination factor 1 [ Homo sapiens ]
Official Symbol : ETF1
Synonyms : ETF1; eukaryotic translation termination factor 1; ERF, ERF1, SUP45L1; eukaryotic peptide chain release factor subunit 1; eRF1; polypeptide chain release factor 1; RF1; sup45 (yeast omnipotent suppressor 45) homolog like 1; TB3 1; protein Cl1; eukaryotic release factor 1; sup45 (yeast omnipotent suppressor 45) homolog-like 1; ERF; ERF1; TB3-1; D5S1995; SUP45L1; MGC111066;
Gene ID : 2107
mRNA Refseq : NM_004730
Protein Refseq : NP_004721
MIM : 600285
UniProt ID : P62495

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any ongoing clinical trials related to ETF1 protein disorders? 04/25/2023

There may be clinical trials evaluating potential treatments or interventions for ETF1 protein disorders, and individuals and families affected by these disorders can consider participating in such trials.

What are the symptoms of metabolic disorders caused by ETF1 protein dysfunction? 06/18/2022

Symptoms may include muscle weakness, lethargy, hypoglycemia, metabolic acidosis, and in some cases, developmental delays and neurological symptoms.

Can ETF1 protein disorders be detected before birth? 05/15/2019

Yes, prenatal testing through genetic screening can detect mutations in the ETF1 gene, allowing for early intervention and management.

How are ETF1 protein disorders diagnosed? 07/05/2018

Diagnosis typically involves biochemical testing, genetic testing, and metabolic screening to identify abnormalities in fatty acid metabolism.

Can ETF1 protein disorders affect individuals of all ages? 02/09/2017

Yes, ETF1 protein disorders can affect individuals of all ages, from newborns to adults, and may present with different symptoms at different stages of life.

Customer Reviews (3)

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Reviews
11/25/2022

    What sets this protein apart is the outstanding technical support provided by the manufacturer.

    09/20/2022

      Its versatility allows me to explore its diverse roles in various biochemical and biological processes accurately.

      07/18/2019

        The ETF1 Protein is of exceptional quality and is precisely tailored to meet my experimental requirements.

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